{"id":1235,"date":"2023-11-16T09:05:39","date_gmt":"2023-11-16T09:05:39","guid":{"rendered":"https:\/\/fermentorchina.com\/?post_type=product&#038;p=1235"},"modified":"2025-07-21T01:37:03","modified_gmt":"2025-07-21T01:37:03","slug":"4union-mechanical-agitation-bioreactorin-situ","status":"publish","type":"product","link":"https:\/\/fermentorchina.com\/es\/products\/4union-mechanical-agitation-bioreactorin-situ\/","title":{"rendered":"Biorreactor de agitaci\u00f3n mec\u00e1nica 4union (in situ)"},"content":{"rendered":"<h1><strong>Revolutionize Parallel Bioprocessing with the 4union mechanical agitation bioreactor (in situ)<\/strong><\/h1>\n<p>Can you imagine actually running multiple fermentations at one time without any equipment or lab redundancy? Consider performing four sharply controlled, parallel experiments all out of one, small device. That\u2019s the power of the <strong>4union mechanical agitation bioreactor (in situ)<\/strong>\u00a0from <a href=\"https:\/\/fermentorchina.com\/es\/contact-us\/\"><u>Biograf\u00eda de BaiLun<\/u><\/a>.<\/p>\n<p>This bioreactor comes sterilization in-situ, uses a four integrated vessels and intelligent control that enables it to provide efficiency, accuracy and convenient all in a sleek modular design. Are you ready to find out how this system will revolutionize the scope of your lab?<\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter  wp-image-1238\" src=\"https:\/\/fermentorchina.com\/wp-content\/uploads\/2023\/11\/On-situ-sterilization-fermenter2-768x1024.jpg\" alt=\"\" width=\"575\" height=\"767\" srcset=\"https:\/\/fermentorchina.com\/wp-content\/uploads\/2023\/11\/On-situ-sterilization-fermenter2-768x1024.jpg 768w, https:\/\/fermentorchina.com\/wp-content\/uploads\/2023\/11\/On-situ-sterilization-fermenter2-225x300.jpg 225w, https:\/\/fermentorchina.com\/wp-content\/uploads\/2023\/11\/On-situ-sterilization-fermenter2-1152x1536.jpg 1152w, https:\/\/fermentorchina.com\/wp-content\/uploads\/2023\/11\/On-situ-sterilization-fermenter2-1536x2048.jpg 1536w, https:\/\/fermentorchina.com\/wp-content\/uploads\/2023\/11\/On-situ-sterilization-fermenter2-9x12.jpg 9w, https:\/\/fermentorchina.com\/wp-content\/uploads\/2023\/11\/On-situ-sterilization-fermenter2-600x800.jpg 600w, https:\/\/fermentorchina.com\/wp-content\/uploads\/2023\/11\/On-situ-sterilization-fermenter2-scaled.jpg 1920w\" sizes=\"(max-width: 575px) 100vw, 575px\" \/><\/p>\n<h2><strong>What Makes The 4union Mechanical Agitation Bioreactor (In Situ) A Game-Changer?<\/strong><\/h2>\n<p>There were four separate vessels constructed out of glass each having its own plate, and four experiments could be run simultaneously with no additional floor space.<\/p>\n<ul>\n<li>In\u2011situ sterilization (SIP) eliminates the need for time-consuming autoclave runs, reducing downtime and contamination risk.<\/li>\n<li>Siemens PLC touchscreen control enables the program, surveillance and recording of various parameters with simplicity.<\/li>\n<li>Agitation may be customized, mechanical, magnetic, to accommodate shear-sensitive cultures, or aggressive gas transfer schemes.<\/li>\n<\/ul>\n<p>Briefly, the bioreactor is that which saves you time, space and budget as well as increasing the data quality and throughput.<\/p>\n<h2><strong>How Can This System Propel Your Research Forward?<\/strong><\/h2>\n<ul>\n<li><strong>Parallel strain screening:<\/strong>compare four microbial or cell lines in distinct conditions.<\/li>\n<li><strong>Media optimization:<\/strong>To test several feed strategies and\/or nutrient mixes or induction times at the same time.<\/li>\n<li><strong>Vaccine generation:<\/strong>Compare the formulations or cell lines more rapidly by growing 4 formulations or cell lines parallel.<\/li>\n<li><strong>Production of enzymes:<\/strong>Optimize agitation, pH, DO and temperature at once vessel to vessel.<\/li>\n<li><strong>Educational:<\/strong>show the principles of fermentation in similar conditions in college workrooms.<\/li>\n<\/ul>\n<p>Curious how it fits into your workflow? Let\u2019s explore the details.<\/p>\n<h2><strong>Specifications Table<\/strong><\/h2>\n<table>\n<tbody>\n<tr>\n<td><strong><b>PARAMETER<\/b><\/strong><\/td>\n<td><strong><b>DESCRIPTION<\/b><\/strong><\/td>\n<\/tr>\n<tr>\n<td><strong><b>Volumen total<\/b><\/strong><\/td>\n<td>0.2\u202fL, 0.5\u202fL, 1\u202fL, 2\u202fL, 3\u202fL, 5\u202fL, 10\u202fL, 20\u202fL, 30\u202fL, 40\u202fL<\/td>\n<\/tr>\n<tr>\n<td><strong><b>Volumen de trabajo<\/b><\/strong><\/td>\n<td>50\u202f%\u201370\u202f%<\/td>\n<\/tr>\n<tr>\n<td><strong><b>Tanque<\/b><\/strong><\/td>\n<td>Borosilicate glass with stainless steel 316L bottom; lid with multiple ports and integrated condenser<\/td>\n<\/tr>\n<tr>\n<td><strong><b>Stirring<\/b><\/strong><\/td>\n<td>Mechanical drive (GJ type, top-mounted) or Magnetic drive (GC, top\/bottom); includes 3 six\u001eblade paddles + foam breaker; adjustable paddle height<\/td>\n<\/tr>\n<tr>\n<td><strong><b>Stirring speed<\/b><\/strong><\/td>\n<td>50\u20131000\u202frpm (mechanical); 50\u2013500\u202frpm (magnetic)<\/td>\n<\/tr>\n<tr>\n<td><strong><b>Esterilizaci\u00f3n<\/b><\/strong><\/td>\n<td>In\u001esitu sterilization system (SIP), no vessel removal required<\/td>\n<\/tr>\n<tr>\n<td><strong><b>control de gases<\/b><\/strong><\/td>\n<td>Rotor meter, air flow 1\u20132\u202fvvm<\/td>\n<\/tr>\n<tr>\n<td><strong><b>Feeding system<\/b><\/strong><\/td>\n<td>Peristaltic pump for automatic feeding of medium, acid, base, and antifoamer<\/td>\n<\/tr>\n<tr>\n<td><strong><b>Anti\u001efoam<\/b><\/strong><\/td>\n<td>Automatic antifoamer dosing via peristaltic pump<\/td>\n<\/tr>\n<tr>\n<td><strong><b>Control de temperatura<\/b><\/strong><\/td>\n<td>Electric jacket-in\/water-source heating; temperature range 5\u202f\u00b0C to 70\u202f\u00b0C<\/td>\n<\/tr>\n<tr>\n<td><strong><b>pH control<\/b><\/strong><\/td>\n<td>Range 2.00\u201312.00 \u00b10.1; auto-adjust via acid\/base pumps; sensors from Hamilton\/Mettler, Switzerland<\/td>\n<\/tr>\n<tr>\n<td><strong><b>HACER control<\/b><\/strong><\/td>\n<td>0\u2013150\u202f% \u00b13\u202f%, resolution 0.1\u202f%; DO sensors from Hamilton\/Mettler; control integrated with stirring and gas flow<\/td>\n<\/tr>\n<tr>\n<td><strong><b>Muestreo<\/b><\/strong><\/td>\n<td>Manual sampling via sterile ports<\/td>\n<\/tr>\n<tr>\n<td><strong><b>Sistema de control<\/b><\/strong><\/td>\n<td>Siemens PLC with 10\u2033 or 15\u2033 touchscreen; monitors stirring, pH, DO, temperature, feeding, gas flow, and alarms; supports data logging\/export; EN\/RU\/CN<\/td>\n<\/tr>\n<tr>\n<td><strong><b>Optional configurations<\/b><\/strong><\/td>\n<td>Remote control, mass flow meters, O\u2082\/N\u2082\/CO\u2082 mixing, CO\u2082 exhaust analysis, level sensor, turbidity (OD) sensor, ORP sensor, weighing, biomass sensors, printing<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><strong>Explore the Power of Four<\/strong><\/h2>\n<h3><strong>Four Vessels, One Controller<\/strong><\/h3>\n<p>Do you want different media in each unit? Different strains? Unique temperature profiles? The <strong>4union mechanical agitation bioreactor (in situ)<\/strong>\u00a0lets each vessel run its own program, all while you monitor them from a single interface.<\/p>\n<p>Such flexibility shortens discovery, and weeks of experimentation and reporting are spared.<\/p>\n<p><img decoding=\"async\" class=\"aligncenter  wp-image-1237\" src=\"https:\/\/fermentorchina.com\/wp-content\/uploads\/2023\/11\/On-situ-sterilization-fermenter1-768x1024.jpg\" alt=\"\" width=\"551\" height=\"735\" srcset=\"https:\/\/fermentorchina.com\/wp-content\/uploads\/2023\/11\/On-situ-sterilization-fermenter1-768x1024.jpg 768w, https:\/\/fermentorchina.com\/wp-content\/uploads\/2023\/11\/On-situ-sterilization-fermenter1-225x300.jpg 225w, https:\/\/fermentorchina.com\/wp-content\/uploads\/2023\/11\/On-situ-sterilization-fermenter1-1152x1536.jpg 1152w, https:\/\/fermentorchina.com\/wp-content\/uploads\/2023\/11\/On-situ-sterilization-fermenter1-1536x2048.jpg 1536w, https:\/\/fermentorchina.com\/wp-content\/uploads\/2023\/11\/On-situ-sterilization-fermenter1-9x12.jpg 9w, https:\/\/fermentorchina.com\/wp-content\/uploads\/2023\/11\/On-situ-sterilization-fermenter1-600x800.jpg 600w, https:\/\/fermentorchina.com\/wp-content\/uploads\/2023\/11\/On-situ-sterilization-fermenter1-scaled.jpg 1920w\" sizes=\"(max-width: 551px) 100vw, 551px\" \/><\/p>\n<h3><strong>Sterilize While You Sleep<\/strong><\/h3>\n<p>Who has time to autoclave vessels in batches? The <strong>4union mechanical agitation bioreactor (in situ)<\/strong>\u00a0\u00a0includes fully integrated in-situ sterilization. All you have to do is connect steam, tap the sterilize and allow the system to do the rest without having to touch the glassware. Ready for use immediately, no downtime.<\/p>\n<h2><strong>Smarter Control for Smarter Science<\/strong><\/h2>\n<h3><strong>Programmable Siemens PLC<\/strong><\/h3>\n<ul>\n<li><strong>10\u2033 or 15\u2033 touchscreen:<\/strong>with intuitive menus<\/li>\n<li><strong>Live dashboards:<\/strong>stirring, DO, pH, temperature, gas, feeding trends<\/li>\n<li><strong>Data export:<\/strong>USB or network connectivity<\/li>\n<li><strong>Languages:<\/strong>English, Russian, Chinese<\/li>\n<li><strong>Alarm setup:<\/strong>thresholds for each vessel<\/li>\n<li><strong>Automated logic:<\/strong>foam, pH shifts trigger immediate dosing<\/li>\n<\/ul>\n<h3><strong>Precision Stirring for Every Culture<\/strong><\/h3>\n<p>Prefer low shear for CHO cells? Choose the magnetic drive with gentle blending. Need high oxygen transfer for yeast? Select the mechanical drive with maximum rpm and the best set of impeller.<\/p>\n<h2><strong>Is This for You?<\/strong><\/h2>\n<p>\u2705\u00a0Universities teaching bioprocess engineering<\/p>\n<p>\u2705\u00a0R&amp;D teams scaling microbial or mammalian processes<\/p>\n<p>\u2705\u00a0Pharma\/vaccine labs running cell line development<\/p>\n<p>\u2705\u00a0Enzyme and bioactive compound producers<\/p>\n<p>This system is flexible to new projects and culture as well as regulatory requirements. It\u2019s flexible on paper, and flexible for your lab.<\/p>\n<h2><strong>Real-Time Monitoring Made Simple<\/strong><\/h2>\n<p>Compare the four possible cultures in one display each having their own data feed:<\/p>\n<ul>\n<li>Live trend charts show DO, pH, temp, RPM<\/li>\n<li>Alarm logs capture anomalies across runs<\/li>\n<li>Downloadable logs support compliance and analysis<\/li>\n<\/ul>\n<p>You can add even remote access to monitor your runs wherever you are.<\/p>\n<h2><strong>Your Lab, Simplified<\/strong><\/h2>\n<ul>\n<li>Install the cabinet and connect utilities (steam, water, compressed air).<\/li>\n<li>Define individual run parameters via touchscreen.<\/li>\n<li>Sterilize in place, no more autoclave queues.<\/li>\n<li>Inoculate each vessel as required.<\/li>\n<li>Monitor real-time conditions on the live interface.<\/li>\n<li>Sample via sterile ports whenever needed.<\/li>\n<li>Shutdown &amp; clean using guided SIP\/CIP sequences.<\/li>\n<li>Extract data for analysis and reporting.<\/li>\n<\/ul>\n<h2><strong>Why Choose the 4union mechanical agitation bioreactor (in situ)?<\/strong><\/h2>\n<ul>\n<li>Parallel experimentation without extra bench space<\/li>\n<li>Integrated sterilization saves hours per cycle<\/li>\n<li>Full automation means you can work smarter, not harder<\/li>\n<li>Modularity allows you to expand the research and expand the system accordingly<\/li>\n<li>Superior data capture ensures reproducibility and regulatory readiness<\/li>\n<\/ul>\n<h2><strong>Ready to Upgrade Your Lab?<\/strong><\/h2>\n<p>The 4union mechanical agitation bioreactor (in situ) is more than a bioreactor, it\u2019s a productivity partner, a data hub, and a research accelerator.<\/p>\n<p>Visit the <a href=\"https:\/\/fermentorchina.com\/es\/products\/\"><u>product page at BaiLun Bio<\/u><\/a>\u00a0to:<\/p>\n<ul>\n<li>Select vessel volumes and drives<\/li>\n<li>Add optional sensors or remote features<\/li>\n<li>Request a quote or live demo<\/li>\n<li>Download datasheets or training guides<\/li>\n<\/ul>\n<h2><strong>Concluding Thoughts<\/strong><\/h2>\n<p>In today\u2019s research environment, speed matters, but so does quality. With four independent vessels, in\u2011situ sterilization, modular sensors, and digital control, the 4union mechanical agitation bioreactor (in situ) delivers both. It is the smarter, quicker, more connected answer to the modern fermentation labs.<\/p>\n<p><strong><em>Ready to triple your throughput without tripling your space? Let <\/em><\/strong><a href=\"https:\/\/fermentorchina.com\/es\/contact-us\/\"><strong><em><u>Biograf\u00eda de BaiLun<\/u><\/em><\/strong><\/a><strong><em>\u00a0help you maximize efficiency, starting today.<\/em><\/strong><\/p>\n<h2><strong>Preguntas frecuentes <\/strong><\/h2>\n<p><strong>Q1: Are vessels interchangeable?<\/strong><\/p>\n<p>Absolutely. Select the size between 0.2 and 40L and set drives and sensors according to the purpose of the vessel.<\/p>\n<p><strong>Q2: How is sterilization performed?<\/strong><\/p>\n<p>The in-situ steam sterilization in the cabinet- now all you have to do is hook up your steam line and start SIP.<\/p>\n<p><strong>Q3: Can stirring modes mix?<\/strong><\/p>\n<p>Yes. The vessels should be configured into mechanical and magnetic heads to satisfy different needs in culture.<\/p>\n<p><strong>Q4: Can I add biomass or OD sensors later?<\/strong><\/p>\n<p>Yes, use the molded lid ports to optionally have sensors such as turbidity, ORP, biomass, temperature probes or level detectors.<\/p>\n<p><strong>Q5: Is remote control available?<\/strong><\/p>\n<p>Yes. Add-ons allow adding network access, remote batch control and data export capabilities.<\/p>","protected":false},"excerpt":{"rendered":"<p>Revolutionize Parallel Bioprocessing with the 4union mechanical agitation bioreactor (in situ) Can you imagine actually running multiple fermentations at one time without any equipment or lab redundancy? Consider performing four sharply controlled, parallel experiments all out of one, small device. That\u2019s the power of the 4union mechanical agitation bioreactor (in situ)\u00a0from BaiLun Bio. This bioreactor [&hellip;]<\/p>\n","protected":false},"featured_media":1236,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[27],"product_tag":[],"class_list":{"0":"post-1235","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-glass-parallelmultistage-fermentor","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product\/1235","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/types\/product"}],"version-history":[{"count":2,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product\/1235\/revisions"}],"predecessor-version":[{"id":6612,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product\/1235\/revisions\/6612"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/media\/1236"}],"wp:attachment":[{"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/media?parent=1235"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product_brand?post=1235"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product_cat?post=1235"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product_tag?post=1235"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}