{"id":1263,"date":"2023-11-17T02:31:13","date_gmt":"2023-11-17T02:31:13","guid":{"rendered":"https:\/\/fermentorchina.com\/?post_type=product&#038;p=1263"},"modified":"2025-11-07T02:38:17","modified_gmt":"2025-11-07T02:38:17","slug":"industrial-scale-fermenter-5000l","status":"publish","type":"product","link":"https:\/\/fermentorchina.com\/es\/products\/industrial-scale-fermenter-5000l\/","title":{"rendered":"Introducing the Industrial Scale Fermenter\/Bioreactor"},"content":{"rendered":"<p>So why is this <strong>Fermentador\/biorreactor a escala industrial<\/strong>\u00a0the heartbeat to so many productive bioprocessing plants? So how about we examine up close.<\/p>\n<h2><strong>The Industrial-Strength of Biotechnology<\/strong><\/h2>\n<p>With any industrial manufacture of product, be it enzymes, vaccines, antibiotics, proteins, bio-based chemicals, the fermenter is more than a piece of equipment. It is that important link between raw materials and finished products.<\/p>\n<p>The Industrial Scale Fermenter\/Bioreactor is a specifically designed product to do this task that supports batch, fed batch or continuous operation and it can be sterile, efficient and reproducible. Envision a high quality, high power automation controlled design and flexibility in a fermenter but with an industry robust 5000L; and you have the dream come true. That is what we bring about.<\/p>\n<h2><strong>What Is Important about Industrial-Scale Fermentation?<\/strong><\/h2>\n<p>When it comes to the active field of biotechnology and industrial microbiology, the biggest challenge, to say the least, is making the necessary scale-up process from the laboratory bench to the full-scale production. A successful pilot run means nothing if your industrial system can&#8217;t replicate those results reliably. Here the <strong>Fermentador\/biorreactor a escala industrial <\/strong>will perform the best, which is the integration of process control, rugged, and simple to clean and sterilize all in one solution.<\/p>\n<p>Does your manufacturing line have problems such as contamination, uneven yields or energy wastage? Now, how does this bioreactor assist in breaking such boundaries?<\/p>\n<h2><strong>The Outstanding Functions and Design<\/strong><\/h2>\n<p>The philosophy of the design is straightforward for our <strong>Fermentador\/biorreactor a escala industrial<\/strong>: no detail is too small, yet should have been optimized to support microbial or cell cultures with maximum productivity and safety. These are the important aspects of the design to consider:<\/p>\n<ul>\n<li>316\/304 stainless steel jacketed tanks with polished service side to 0.4-0.6 microns to enable clearance and low contamination chance.<\/li>\n<li>Advanced stirring systems (mechanical or magnetic) to handle different viscosity media and delicate cultures.<\/li>\n<li>Fully automated SIP (sterilization in place) and CIP (cleaning in place) systems to reduce downtime.<\/li>\n<li>Siemens PLC control and online control of real-time storage, monitoring of data and advanced control techniques.<\/li>\n<li>Adjustable gas control covering Air, O2, N2 and CO2.<\/li>\n<\/ul>\n<p>And now you will ask me how this can be of any practical assistance in training? Let us go more into details.<\/p>\n<h2><strong>Technical Parameters<\/strong><\/h2>\n<p>What makes the <strong>Fermentador\/biorreactor a escala industrial <\/strong>a production ready solution is as follows:<\/p>\n<table style=\"font-size: 16px; font-style: normal;\">\n<tbody>\n<tr>\n<td width=\"318\"><strong><b>Par\u00e1metro<\/b><\/strong><\/td>\n<td width=\"1066\"><strong><b>D<\/b><\/strong><strong><b>descripci\u00f3n<\/b><\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Volumen total<\/td>\n<td width=\"1066\">5L, 10L, 15L, 20L, 30L, 50L, 100L, 200L, 500L, 1000L, 5KL, 50KL, 200KL, etc.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Volumen de trabajo<\/td>\n<td width=\"1066\">30%~70%<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Tanque<\/td>\n<td width=\"1066\"><a href=\"https:\/\/www.sakysteel.com\/316-stainless-steel-sheet.html\">Tanque con camisa, fabricado con SS316 y SS304, presi\u00f3n de dise\u00f1o del tanque de 0,3 Mpa, presi\u00f3n de dise\u00f1o de la camisa de 0,35 Mpa, pulido de 0,4 a 0,6 um, relaci\u00f3n de di\u00e1metro y altura de 1:2,2 a 2,5<\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Sistema de agitaci\u00f3n<\/td>\n<td width=\"1066\">Accionamiento mec\u00e1nico en la parte superior\/inferior o accionamiento magn\u00e9tico en la parte superior, paleta de seis hojas ajustable en altura de 3 piezas<\/p>\n<p>Velocidad de agitaci\u00f3n: 50~1000rpm\/50-400rpm<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Esterilizaci\u00f3n<\/td>\n<td width=\"1066\">Esterilizar en el lugar (SIP), control autom\u00e1tico por programa<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Limpio<\/td>\n<td width=\"1066\">Limpieza in situ (CIP) mediante bola rociadora<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">control de gases<\/td>\n<td width=\"1066\">Control por medidor de rotor, caudal de aire 1 vvm<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Alimentaci\u00f3n<\/td>\n<td width=\"1066\">Alimentaci\u00f3n autom\u00e1tica mediante bomba perist\u00e1ltica.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Control antiespumante<\/td>\n<td width=\"1066\">Agregue antiespumante autom\u00e1ticamente mediante bomba perist\u00e1ltica<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Control de temperatura<\/td>\n<td width=\"1066\">Autocontrol, rango de calefacci\u00f3n el\u00e9ctrica: la fuente de agua agrega 5 \u2103 a 70 \u2103<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">control de ph<\/td>\n<td width=\"1066\">PH 2,00-12,00\u00b10,1, control autom\u00e1tico de adici\u00f3n de \u00e1cido\/base mediante bomba perist\u00e1ltica, sensor de pH de Hamilton\/Mettler, Suiza.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">hacer control<\/td>\n<td width=\"1066\">0-150\u00b13% que muestra una precisi\u00f3n de 0,1%, sensor de OD de Hamilton\/Mettler, Suiza. HACER acoplamiento con agitaci\u00f3n, ox\u00edgeno.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Muestreo<\/td>\n<td width=\"1066\">V\u00e1lvula de muestreo, esterilizaci\u00f3n de botes por separado, manual.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Cosecha<\/td>\n<td width=\"1066\">V\u00e1lvula inferior de zona muerta cero (Gemu\/Burket, Alemania), esterilizaci\u00f3n de latas por separado, manual\/autom\u00e1tica<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Sistema de elevaci\u00f3n de tapa<\/td>\n<td width=\"1066\">30L-500L tienen sistema de elevaci\u00f3n de tapa, 700-1000L tienen agujero humano.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Presi\u00f3n<\/td>\n<td width=\"1066\">Control autom\u00e1tico, transmisor de presi\u00f3n BD Alemania<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Escape<\/td>\n<td width=\"1066\">Disponer de condensador antes del escape, control mediante v\u00e1lvula de diagrama\/v\u00e1lvula de control proporcional.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Par\u00e1metros de control<\/td>\n<td width=\"1066\">Pantalla t\u00e1ctil de 10 o 15 pulgadas, PLC Siemens con par\u00e1metros de control (agitaci\u00f3n, pH, OD, temperatura, alimentaci\u00f3n, alarma, gas, etc.), an\u00e1lisis de datos, registro de datos, salida de datos, idioma (RU\/EN\/CN) y otros personalizados. funciones<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Configuraci\u00f3n opcional<\/td>\n<td width=\"1066\">Control remoto, medidor de flujo m\u00e1sico (gas de control autom\u00e1tico), O2\/N2\/CO2, flujo de gas 2vvm, an\u00e1lisis de escape de gas (CO2), sensor de nivel, sensor de turbidez (OD), sensor de ORP, sistema de peso, sensor de celda viva (biomasa) , Impresi\u00f3n, Pantalla t\u00e1ctil Siemens, Doble sello mec\u00e1nico, Grupo de 4 v\u00e1lvulas para alimentaci\u00f3n, Descarga autom\u00e1tica de v\u00e1lvula inferior, Certificado ASME, Certificado CSA, Cultivo por lotes, Transferencia de semillas, etc.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><strong>Process Reliability: The Center-piece of Industrial Manufacture<\/strong><\/h2>\n<p>Consider the bets: a contaminated 5000L fermenter will result in massive material loss and time wastage. Such issues are avoided by this system in the following way:<\/p>\n<ul>\n<li>Many smooth inside welds and smooth polished interiors in order to avoid dead corners.<\/li>\n<li>SIP and CIP systems that are completely automated with assurance of effective sterilization and cleaning.<\/li>\n<li>Alarm system and sensor integration to detect the deviations in the process in real time.<\/li>\n<\/ul>\n<p>Today, ask yourself how much money you would save only by eliminating even one case of contamination per year.<\/p>\n<h2><strong>State-of-Art Automation and Control<\/strong><\/h2>\n<p>El <strong>Fermentador\/biorreactor a escala industrial <\/strong>does not only provide strong mechanical design, but it also provides the best control available in the industry:<\/p>\n<ul>\n<li>The Siemens PLCs coupled with touch screens easy to use.<\/li>\n<li>The parameters such as pH, DO, temperature and agitation speed could be monitored in real time.<\/li>\n<li>Compliance and optimisation of process with data logging and export.<\/li>\n<li>Automatic feeding and antifoam to get stable production.<\/li>\n<\/ul>\n<p>This implies that your operators have to make fewer setting changes, and more time enhancing process results.<\/p>\n<h2><strong>Flexible Stirring and Gas handling<\/strong><\/h2>\n<p>The system is appropriate to both mechanical and magnetic stirring, all the way to highly viscous fungal cultures as well as shear-sensitive mammalian cells:<\/p>\n<ul>\n<li>Sealed operation is guaranteed as there is magnetic coupling which minimizes the chances of any contamination.<\/li>\n<li>Paddles are six bladed to maximize the mixing and oxygen transfer.<\/li>\n<li>Gas control aids the sophisticated applications:<\/li>\n<li>Inputs of air, oxygen, nitrogen and CO2.<\/li>\n<li>Auto gas blending optional mass flow meters.<\/li>\n<li>Exhaust condenser ensures that the products are not lost and minimizes vents.<\/li>\n<\/ul>\n<h2><strong>Versatility and Scalability of Production <\/strong><\/h2>\n<p>The BODREAD V2 system is a versatile and scalable medium-sized production grid. Regardless of the type of product you are yielding, antibiotics, amino acids, vaccines, or enzymes, the <strong>Fermentador\/biorreactor a escala industrial <\/strong>is versatile on the basis of process modes:<\/p>\n<ul>\n<li>Batch culture.<\/li>\n<li>Fed-batch culture.<\/li>\n<li>Continuous and perfusion system.<\/li>\n<\/ul>\n<p>An optional module, such as live cell sensors, weight systems and ORP sensors, enables you to optimize your process.<\/p>\n<h2><strong>Construction to World standards<\/strong><\/h2>\n<p>The system is trans-national market oriented:<\/p>\n<ul>\n<li>Options of certification to ASME and CSA.<\/li>\n<li>Brand-name components; Siemens, Hamilton, Mettler, Gemu, Burket, and BD.<\/li>\n<li>Interface language and Software customization.<\/li>\n<\/ul>\n<p>Not only has been built to work-but to do it so well wherever you are operating.<\/p>\n<h2><strong>The Energy efficiency and Sustainability<\/strong><\/h2>\n<p>The cost of energy may be a huge challenge to profitability. There is a jacketed design and effective heating and cooling that save on thermal loss. The CIP system diminishes use of water and cleaning agent.<\/p>\n<p>Consider this: what could happen to utility expenses should your fermenter cut on the cost of utilities without affecting performance?<\/p>\n<h2><strong>Applications of It in the Real World<\/strong><\/h2>\n<p>How are <strong>Fermentador\/biorreactor a escala industrial <\/strong>used by the industries?<\/p>\n<ul>\n<li>Vaccine manufacturing (human and veterinary).<\/li>\n<li>The manufacture of enzymes into food and industry.<\/li>\n<li>Organic acid and amino acids.<\/li>\n<li>Antibiotic fermentation.<\/li>\n<li>Recombinant proteins manufacture.<\/li>\n<\/ul>\n<p>It is so versatile that it underpins both multinational production plants and the biotech startups.<\/p>\n<h2><strong>Intuitive Operation: Operator based Design<\/strong><\/h2>\n<p>Usability can provide to any system even the most advanced one:<\/p>\n<ul>\n<li>Easy-to-read displays having 10-15inch touch screens.<\/li>\n<li>Multi-lingual menu and graphical data presentations.<\/li>\n<li>Monitoring remotely eliminates the requirement of people on the locations.<\/li>\n<li>The curves of historical data are used to debug the processes and minimize flaws.<\/li>\n<\/ul>\n<p>How many hours would your team have saved on a user-friendly system?<\/p>\n<h2><strong>On-the-fly Safety and Compliance<\/strong><\/h2>\n<p>Interlocked and built-in warnings safeguard your goods, machines and employees:<\/p>\n<ul>\n<li>Overpressure automatic shut-to-off.<\/li>\n<li>Alerts over temperature, pH and DO variances.<\/li>\n<li>Convenience in export of data in regulatory audits.<\/li>\n<li>Nothing unexpected except stable production.<\/li>\n<li>Viable investment in the future<\/li>\n<\/ul>\n<p>Your production requirements can increase. You can get the modular structure of the <strong>Industrial Scale Fermenter\/Bioreactor:<\/strong><\/p>\n<ul>\n<li>Mass flow control as opposed to rotor meter.<\/li>\n<li>Include exhausts gas analysis CO2.<\/li>\n<li>Install level sensors, turbidity and biomass sensors.<\/li>\n<li>Increase in single batch to seed transfer systems.<\/li>\n<li>It is a system that is scalable with your business.<\/li>\n<\/ul>\n<h2><strong>Why BaiLun Bio?<\/strong><\/h2>\n<p>With decades of experience <a href=\"https:\/\/fermentorchina.com\/es\/contact-us\/\"><u>Biograf\u00eda de BaiLun<\/u><\/a>\u00a0only supplies equipment:<\/p>\n<ul>\n<li>Consulting and design of processes.<\/li>\n<li>After sale services and training.<\/li>\n<li>Globally shipping and set up.<\/li>\n<li>Custom made remedies to unique use.<\/li>\n<\/ul>\n<p>We understand fermentation isn&#8217;t just equipment, it&#8217;s your business.<\/p>\n<h2><strong>Reflexiones finales<\/strong><\/h2>\n<p>El <strong>Fermentador\/biorreactor a escala industrial <\/strong>is not a product only. It is the man to:<\/p>\n<ul>\n<li>Increases of the yields of products.<\/li>\n<li>Unity in quality of batches.<\/li>\n<li>Reduced downtimes and reduction of contamination.<\/li>\n<li>Energy and resources efficiency.<\/li>\n<li>Easy to use control.<\/li>\n<\/ul>\n<p>Ask yourself the question: is your process more cost effective, prolific, and profitable with improved equipment?<\/p>\n<p>It is time to make your production to the next level. <a href=\"https:\/\/fermentorchina.com\/es\/contact-us\/\"><u>Contacto BaiLun Biograf\u00eda<\/u><\/a>\u00a0to understand how the <strong>Fermentador\/biorreactor a escala industrial <\/strong>can create wonders in your operations.<\/p>\n<p>Are you craving to grow with confidence? How about we create fermentation of the future.<\/p>","protected":false},"excerpt":{"rendered":"<p>Take a look at the best solution to big-scale, high-efficient, and stable fermentation, the <strong>Fermentador\/biorreactor a escala industrial<\/strong>\u00a0that BaiLun Bio provides. The powerhouse will suit the needs of people who seek a high level of performance without concessions: it is a place where innovation in engineering and flexibility of operations meet the rigor of quality.<\/p>","protected":false},"featured_media":3258,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[40,22],"product_tag":[],"class_list":{"0":"post-1263","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-hot-products","7":"product_cat-industrial-bioreactor-fermenter","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product\/1263","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/types\/product"}],"version-history":[{"count":3,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product\/1263\/revisions"}],"predecessor-version":[{"id":7047,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product\/1263\/revisions\/7047"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/media\/3258"}],"wp:attachment":[{"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/media?parent=1263"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product_brand?post=1263"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product_cat?post=1263"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product_tag?post=1263"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}