{"id":927,"date":"2023-10-11T06:33:58","date_gmt":"2023-10-11T06:33:58","guid":{"rendered":"https:\/\/fermentorchina.com\/?post_type=product&#038;p=927"},"modified":"2025-11-14T06:30:57","modified_gmt":"2025-11-14T06:30:57","slug":"bottom-mechanically-agitated-fermenter","status":"publish","type":"product","link":"https:\/\/fermentorchina.com\/es\/products\/bottom-mechanically-agitated-fermenter\/","title":{"rendered":"100 Liter Stainless Steel Bottom Mechanically Agitated Fermenter BLBIO-100SJB"},"content":{"rendered":"<h2><strong>Designed to Outperform: Why Choose <\/strong><strong>Bottom Mechanically Agitated Fermenter<\/strong><strong>?<\/strong><\/h2>\n<ul>\n<li>All stainless-steel 316L durable, polished stainless steel with hygienic design.<\/li>\n<li>Bottom mechanical stirring- provides stable and even mixing, which is ideal in a variety of cultures.<\/li>\n<li>Completely automated control system powered with Siemens PLC and working on the touchscreen.<\/li>\n<li>Clean-in-place (CIP) &amp; sterilize-in-place (SIP), save time, reduce contamination risk.<\/li>\n<li>Adaptable applications, Fits well with bacteria, yeast, fungus, mammalian and plant cells, vaccines, enzymes and so on.<\/li>\n<\/ul>\n<p>Have you ever experienced any process challenge of inconsistent temperature or oxygen flow? The design of diversion and bottom stirring on this fermenter makes it uniform within the vessel.<\/p>\n<h2><strong>Fermenter Description: What Sets the <\/strong><strong>100 Liter Stainless Steel Bottom Mechanically Agitated Fermenter<\/strong><strong>\u00a0Apart?<\/strong><\/h2>\n<p>El <strong>100 Liter Stainless Steel Bottom Mechanically Agitated Fermenter BLBIO-100SJB<\/strong><strong>\u00a0<\/strong>isn&#8217;t just about volume. With its superior capabilities, it is famous among biotechnology and pharmacology specialists:<\/p>\n<ul>\n<li>Corrosion resistant and simple to clean, all stainless steel 316L tank body.<\/li>\n<li>Steam sterilized: is seen to last longer and offer superior protection through its double mechanical seal.<\/li>\n<li>Special sampling &amp; discharging valves for aseptic processes.<\/li>\n<li>Large viewing glass for real-time observation.<\/li>\n<li>Integrated ports for temperature, pH, DO sensors, and feeding\/inoculation.<\/li>\n<li>Optimized diversion design for better temperature and nutrient distribution.<\/li>\n<li>Air distributor and precision rotameter for accurate gas flow.<\/li>\n<\/ul>\n<p>All welds are done to be strong, neat and fine polished to 0.4-0.6um &#8211; the epitome of beauty and utility.<\/p>\n<h2><strong>Fermenter Technical Specifications<\/strong><\/h2>\n<p>Every performance and reliability that you require, at one glance:<\/p>\n<h2><strong>Bottom Mechanically Agitated Fermenter<\/strong><b> <\/b><strong><b>Par\u00e1metros t\u00e9cnicos:<\/b><\/strong><\/h2>\n<table>\n<tbody>\n<tr>\n<td width=\"318\"><strong><b>Par\u00e1metro<\/b><\/strong><\/td>\n<td width=\"1066\"><strong><b>D<\/b><\/strong><strong><b>descripci\u00f3n<\/b><\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Volumen total<\/td>\n<td width=\"1066\">5L, 10L, 15L, 20L, 30L, 50L, 100L, 200L, 500L, 1000L, 5KL, 50KL, 200KL, etc.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Volumen de trabajo<\/td>\n<td width=\"1066\">30%~70%<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Tanque<\/td>\n<td width=\"1066\">Tanque con camisa, fabricado con SS316 y SS304, presi\u00f3n de dise\u00f1o del tanque de 0,3 Mpa, presi\u00f3n de dise\u00f1o de la camisa de 0,35 Mpa, pulido de 0,4 a 0,6 um, relaci\u00f3n de di\u00e1metro y altura de 1:2,2 a 2,5<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Sistema de agitaci\u00f3n<\/td>\n<td width=\"1066\">Accionamiento mec\u00e1nico en la parte superior\/inferior o accionamiento magn\u00e9tico en la parte superior, paleta de seis hojas ajustable en altura de 3 piezas<\/p>\n<p>Velocidad de agitaci\u00f3n: 50~1000rpm\/50-400rpm<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Esterilizaci\u00f3n<\/td>\n<td width=\"1066\">Esterilizar en el lugar (SIP), control autom\u00e1tico por programa<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Limpio<\/td>\n<td width=\"1066\">Limpieza in situ (CIP) mediante bola rociadora<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">control de gases<\/td>\n<td width=\"1066\">Control por medidor de rotor, caudal de aire 1 vvm<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Alimentaci\u00f3n<\/td>\n<td width=\"1066\">Alimentaci\u00f3n autom\u00e1tica mediante bomba perist\u00e1ltica.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Control antiespumante<\/td>\n<td width=\"1066\">Agregue antiespumante autom\u00e1ticamente mediante bomba perist\u00e1ltica<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Control de temperatura<\/td>\n<td width=\"1066\">Autocontrol, rango de calefacci\u00f3n el\u00e9ctrica: la fuente de agua agrega 5 \u2103 a 70 \u2103<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">control de ph<\/td>\n<td width=\"1066\">PH 2,00-12,00\u00b10,1, control autom\u00e1tico de adici\u00f3n de \u00e1cido\/base mediante bomba perist\u00e1ltica, sensor de pH de Hamilton\/Mettler, Suiza.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">hacer control<\/td>\n<td width=\"1066\">0-150\u00b13% que muestra una precisi\u00f3n de 0,1%, sensor de OD de Hamilton\/Mettler, Suiza. HACER acoplamiento con agitaci\u00f3n, ox\u00edgeno.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Muestreo<\/td>\n<td width=\"1066\">V\u00e1lvula de muestreo, esterilizaci\u00f3n de botes por separado, manual.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Cosecha<\/td>\n<td width=\"1066\">V\u00e1lvula inferior de zona muerta cero (Gemu\/Burket, Alemania), esterilizaci\u00f3n de latas por separado, manual\/autom\u00e1tica<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Sistema de elevaci\u00f3n de tapa<\/td>\n<td width=\"1066\">30L-500L tienen sistema de elevaci\u00f3n de tapa, 700-1000L tienen agujero humano.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Presi\u00f3n<\/td>\n<td width=\"1066\">Control autom\u00e1tico, transmisor de presi\u00f3n BD Alemania<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Escape<\/td>\n<td width=\"1066\">Disponer de condensador antes del escape, control mediante v\u00e1lvula de diagrama\/v\u00e1lvula de control proporcional.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Par\u00e1metros de control<\/td>\n<td width=\"1066\">Pantalla t\u00e1ctil de 10 o 15 pulgadas, PLC Siemens con par\u00e1metros de control (agitaci\u00f3n, pH, OD, temperatura, alimentaci\u00f3n, alarma, gas, etc.), an\u00e1lisis de datos, registro de datos, salida de datos, idioma (RU\/EN\/CN) y otros personalizados. funciones<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Configuraci\u00f3n opcional<\/td>\n<td width=\"1066\">Control remoto, medidor de flujo m\u00e1sico (gas de control autom\u00e1tico), O2\/N2\/CO2, flujo de gas 2vvm, an\u00e1lisis de escape de gas (CO2), sensor de nivel, sensor de turbidez (OD), sensor de ORP, sistema de peso, sensor de celda viva (biomasa) , Impresi\u00f3n, Pantalla t\u00e1ctil Siemens, Doble sello mec\u00e1nico, Grupo de 4 v\u00e1lvulas para alimentaci\u00f3n, Descarga autom\u00e1tica de v\u00e1lvula inferior, Certificado ASME, Certificado CSA, Cultivo por lotes, Transferencia de semillas, etc.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><strong>Smart Control with Siemens PLC<\/strong><\/h2>\n<p>Imagine having every critical parameter at your fingertips.<\/p>\n<ul>\n<li>This fermenter incorporates a German Siemens S7-200 type PLC with a 10-inch LCD touchscreen:<\/li>\n<li>View real-time data (pH, DO, temp, stirring speed, gas flow)<\/li>\n<li>Automatic process control<\/li>\n<li>Historical data logging &amp; export<\/li>\n<li>User-friendly interface in English, Chinese, and more<\/li>\n<li>Menu-driven navigation for fast learning curve<\/li>\n<\/ul>\n<p><strong><em>Tired of manual adjustments? Under automated control you concentrate on the results rather than on continuous watching.<\/em><\/strong><\/p>\n<h2><strong>Fermenter Applications<\/strong><\/h2>\n<p>El <strong>100 Liter Stainless Steel Bottom Mechanically Agitated Fermenter BLBIO-100SJB<\/strong><strong>\u00a0<\/strong>can be used:<\/p>\n<h3><strong>Animal vaccine production:<\/strong><\/h3>\n<ul>\n<li>Avian influenza, PRRS, foot-and-mouth, rabies, mink vaccines<\/li>\n<li>DTP, diphtheria, tetanus<\/li>\n<\/ul>\n<h3><strong>Human vaccines:<\/strong><\/h3>\n<p>Meningitis, pneumonia IV, hepatitis B, diphtheria, tetanus<\/p>\n<h3><strong>Other Fermentation Processes:<\/strong><\/h3>\n<ul>\n<li>Bacterial, fungal &amp; yeast cultures<\/li>\n<li>Mammalian cell lines (CHO, HEK293)<\/li>\n<li>Plant cells, algae, enzymes, proteins<\/li>\n<li>Antibiotics, food additives<\/li>\n<\/ul>\n<p>It can be used successfully on R&amp;D to pilot scale due to its perfect mixture and temperature control.<\/p>\n<h2><strong>Bottom Mechanical Stirring: Why It Matters<\/strong><\/h2>\n<p>Bottom mechanical stirring ensures:<\/p>\n<ul>\n<li>Even distribution of heat and nutrients<\/li>\n<li>Reduced vortexing compared to top drives<\/li>\n<li>Better control for shear-sensitive organisms<\/li>\n<li>Stability at varying volumes<\/li>\n<\/ul>\n<p>Ever wondered if bottom stirring fits your process? In cases in which your product will work best under even conditions, bottom stirring can be of great benefit.<\/p>\n<h2><strong>\u00a0Gas &amp; Ventilation: Deep Ventilation Done Right<\/strong><\/h2>\n<ul>\n<li>Integrated air distributor spreads gas evenly.<\/li>\n<li>Rotameter allows fine-tuned manual gas adjustment.<\/li>\n<li>Sterilizing filters (Dominic\/Shanghai Yiming) with 0.2\u03bcm pore prevent contamination.<\/li>\n<li>Steam sterilized condensate cooling keeps seals lubricated and safe.<\/li>\n<li>Outcome: improved oxygen transfers rate, safer usage and a longer equipment functioning life.<\/li>\n<\/ul>\n<h2><strong>Engineered for Hygiene &amp; Durability<\/strong><\/h2>\n<ul>\n<li>All internal welds are smooth &amp; neat.<\/li>\n<li>Polished to Ra \u2264 0.4\u20130.6\u03bcm, reducing contamination risk.<\/li>\n<li>Steam sterilization with automatic temperature control.<\/li>\n<li>2-mechanical seal cooled &amp; lubricated steam condensate.<\/li>\n<\/ul>\n<p>The design reduces the time of cleaning and maintains low batch-to-batch contamination.<\/p>\n<h2><strong>Process Optimization &amp; Scalability<\/strong><\/h2>\n<p>El <strong>100 Liter Stainless Steel Bottom Mechanically Agitated Fermenter BLBIO-100SJB<\/strong><strong>\u00a0<\/strong>is a laboratory-scale up unit:<\/p>\n<ul>\n<li>Equal geometry and mixing at various volumes, processes can be easily validated.<\/li>\n<li>Data logging helps refine your protocols over time.<\/li>\n<li>Remote access options let you monitor anywhere.<\/li>\n<\/ul>\n<p>Ready to move from lab to pilot? This one is your over-bridge that builds 5L to 200KL systems, each one as detailed as the other.<\/p>\n<h2><strong>Optional Configurations &amp; Custom Features<\/strong><\/h2>\n<p>Customize your fermenter to match your exact needs:<\/p>\n<ul>\n<li>Mass flow meter for automatic gas mixing<\/li>\n<li>CO\u2082 exhaust gas analysis<\/li>\n<li>Turbidity, biomass &amp; ORP sensors<\/li>\n<li>Automatic bottom valve discharge<\/li>\n<li>Batch culture &amp; seed transfer modes<\/li>\n<li>Double mechanical seals &amp; 4-valve feeding groups<\/li>\n<li>Certificates: ASME, CSA for Regulatory Compliance<\/li>\n<\/ul>\n<p>Such adaptability maintains your investment up to date as your process changes in the future.<\/p>\n<h2><strong>\u00a0Sustainable Bioprocessing Benefits<\/strong><\/h2>\n<ul>\n<li>Lower water &amp; cleaning agent consumption with CIP\/SIP.<\/li>\n<li>Energy-efficient design.<\/li>\n<li>High durability reduces replacement needs.<\/li>\n<\/ul>\n<p>By investing on quality equipment, the lifecycle cost decreases and the unscheduled startup is minimized.<\/p>\n<h2><strong>Intelligent Design Features <\/strong><\/h2>\n<ul>\n<li>Large viewing window &amp; internal light.<\/li>\n<li>Liquid level interfaces and multiple spare ports.<\/li>\n<li>Compact footprint with lid lift system.<\/li>\n<li>Zero dead zone valve for full drainage.<\/li>\n<\/ul>\n<p>All of this makes your work efficient and your data reliable.<\/p>\n<h2><strong>Real-World Results: What You Can Produce?<\/strong><\/h2>\n<ul>\n<li>Recombinant proteins &amp; enzymes<\/li>\n<li>Vaccines (viral &amp; bacterial)<\/li>\n<li>Cell culture-based products<\/li>\n<li>Algal biomass<\/li>\n<li>Organic acids &amp; amino acids<\/li>\n<li>Antibiotics &amp; therapeutic proteins<\/li>\n<\/ul>\n<p>The fermenter is flexible regardless of whether you need food, pharma, or research products.<\/p>\n<h2><strong>Quick Recap: Why It Stands Out<\/strong><\/h2>\n<ul>\n<li>Robust stainless steel build<\/li>\n<li>Bottom mechanical stirring for stable, even mixing<\/li>\n<li>Automated Siemens PLC control<\/li>\n<li>CIP &amp; SIP for top hygiene<\/li>\n<li>Flexible volumes and applications<\/li>\n<li>Global sensor &amp; valve brands (Hamilton, Gemu, BD, etc.)<\/li>\n<\/ul>\n<p><strong>100 Liter Stainless Steel Bottom Mechanically Agitated Fermenter BLBIO-100SJB<\/strong><strong>\u00a0<\/strong>is not only just a machine, it is a heart of your bioprocess lab.<\/p>\n<h2><strong>Ready to Upgrade Your Fermentation?<\/strong><\/h2>\n<p>Think even quicker scale-up, reduced contamination threat and wiser management of each batch.<\/p>\n<p>Become familiar with <a href=\"https:\/\/fermentorchina.com\/es\/contact-us\/\"><u>Biograf\u00eda de BaiLun<\/u><\/a>, visit the company at the given contact, call today to discuss or have a quote tailored to your own requirements.<\/p>","protected":false},"excerpt":{"rendered":"<p>El <strong>100 Liter Stainless Steel Bottom Mechanically Agitated Fermenter BLBIO-100SJB<\/strong>, relied upon to develop vaccines, create enzymes, cell culture, and more intensive bio processes, this fermenter introduces accuracy in engineering and intelligent control to your line.<\/p>","protected":false},"featured_media":6529,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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