{"id":955,"date":"2023-10-11T06:52:08","date_gmt":"2023-10-11T06:52:08","guid":{"rendered":"https:\/\/fermentorchina.com\/?post_type=product&#038;p=955"},"modified":"2025-11-14T03:32:35","modified_gmt":"2025-11-14T03:32:35","slug":"100l-mammalian-cell-fermenter","status":"publish","type":"product","link":"https:\/\/fermentorchina.com\/es\/products\/100l-mammalian-cell-fermenter\/","title":{"rendered":"100 Liter mammalian cell fermenter BLBIO-100SCUC"},"content":{"rendered":"<p>Have you ever wondered how it would feel to operate your mammalian cell cultures by the use of equipment that promises reproducible results, precision control, and endures the demands of current high technology biotechnology? Let\u2019s dive in.<\/p>\n<h2><strong>An Introduction to Modern Fermentation Excellence<\/strong><\/h2>\n<p>El <strong>100 Liter mammalian cell fermenter BLBIO-100SCUC<\/strong>\u00a0is purpose-built to support the complex requirements of mammalian cell culture, including hybridoma cells, CHO cells, insect cells, and many others. With the battle between reproducibility and process efficiency deciding who wins the race against research and industrial production in the world of biotech nowadays, this fermenter stands the difference.<\/p>\n<p>Designed with the best structural attributes, it offers ultra-performance and has features that meet functionality, adaptability, and ease of use.<\/p>\n<h2><strong>Why Choose the Stainless Steel Design?<\/strong><\/h2>\n<p>&nbsp;<\/p>\n<p>This fermenter is made of high quality 316L stainless steel featuring 304 stainless steel clips and provides the following:<\/p>\n<ul>\n<li>High corrosion resistance, critical for cleanroom and GMP environments.<\/li>\n<li>Internal surface with polished finish of 0.2-0.4um, allowed a reduced chance of contamination and easy cleaning.<\/li>\n<li>Polishing the surface in order to come up with the beauty of a professional finish that shows quality.<\/li>\n<li>The level of smart design it flaunts (blind spots are avoided, even within the tank) make it easier to clean to keep it sterile between run batches and shorten downtime.<\/li>\n<\/ul>\n<p>Are you wasting your time as far as maintaining and cleaning are concerned? A smarter tank design could save you hours.<\/p>\n<h2><strong>Performance Driven by Precise Engineering<\/strong><\/h2>\n<p>At the heart of the <strong>100 Liter mammalian cell fermenter BLBIO-100SCUC<\/strong><strong>\u00a0<\/strong>is a suite of features engineered for performance:<\/p>\n<ul>\n<li>Low shear mixing blades eliminate the possibility of damage to small cells such as delicate mammalian cells, which is a major advantage of this method of stirring.<\/li>\n<li>It has variable stirring speed of 30 -300 rpm which complies with varying culture demands.<\/li>\n<li>The occurrence of contamination is also minimized by the integrated cooling systems and exhaust pathways which have a special designed exhaust pipe ensuring the purity of your cultures.<\/li>\n<\/ul>\n<p>Does your system right now safeguard your cell integrity when you mix it? This fermenter is built to do exactly that.<\/p>\n<h2><strong>Control Systems for Complete Process Oversight<\/strong><\/h2>\n<p>The Siemens S7-200 series PLC and large touch screen interface (10 or 15 inches) provide:<\/p>\n<ul>\n<li>Availability of real time information and room to perform necessary adjustments such as pH, DO, temperature, and gas flow among others.<\/li>\n<li>Full menu-driven operation in English, Russian, or Chinese.<\/li>\n<li>Instead, its strong data logging and data analysis capabilities that transform raw data into the actionable ones.<\/li>\n<\/ul>\n<p>Whole new level of confidence when you can see the performance of your processes on your crystal clear interface, and warnings when important parameters are drifting. Wouldn\u2019t that simplify your daily operation?<\/p>\n<h2><strong>Key Specifications You Can Trust<\/strong><\/h2>\n<p>Let\u2019s explore the technical heart of the <strong>100 Liter mammalian cell fermenter BLBIO-100SCUC<\/strong>:<\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"318\"><strong><b>Par\u00e1metro<\/b><\/strong><\/td>\n<td width=\"1066\"><strong><b>D<\/b><\/strong><strong><b>descripci\u00f3n<\/b><\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Volumen total<\/td>\n<td width=\"1066\">5L, 10L, 15L, 20L, 30L, 50L, 100L, 200L, 500L, 1000L, 5KL, 10KL, etc.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Volumen de trabajo<\/td>\n<td width=\"1066\">30%~70%<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Tanque<\/td>\n<td width=\"1066\">Pulido electrol\u00edtico interior, precisi\u00f3n: 0,2-0,4um.<\/p>\n<p>Relaci\u00f3n di\u00e1metro y altura 1:1,5<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Sistema de agitaci\u00f3n<\/td>\n<td width=\"1066\">Accionamiento magn\u00e9tico, cuchillas mezcladoras de bajo cizallamiento. Velocidad de agitaci\u00f3n: 30~300rpm<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Esterilizaci\u00f3n<\/td>\n<td width=\"1066\">Esterilizaci\u00f3n in situ (SIP), control autom\u00e1tico por programa<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Limpio<\/td>\n<td width=\"1066\">Limpiar en su lugar con una bola rociadora.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">control de gases<\/td>\n<td width=\"1066\">Provisi\u00f3n para mezclar al menos cuatro gases (Aire, Ox\u00edgeno, Nitr\u00f3geno y CO2)<\/p>\n<p>Control autom\u00e1tico por medidor de flujo m\u00e1sico. Flujo de aire 1vvm, O2\/N2\/CO2 0,1vvm.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Alimentaci\u00f3n<\/td>\n<td width=\"1066\">Alimentaci\u00f3n autom\u00e1tica mediante bomba perist\u00e1ltica.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Control antiespumante<\/td>\n<td width=\"1066\">Agregue antiespumante autom\u00e1ticamente mediante bomba perist\u00e1ltica<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Control de temperatura<\/td>\n<td width=\"1066\">Autocontrol, rango de calefacci\u00f3n el\u00e9ctrica: la fuente de agua agrega 5 \u2103 a 70 \u2103<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">control de ph<\/td>\n<td width=\"1066\">PH 2,00-12,00\u00b10,1, control autom\u00e1tico de adici\u00f3n de \u00e1cido\/base mediante bomba perist\u00e1ltica, sensor de pH de Hamilton\/Mettler, Suiza.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">hacer control<\/td>\n<td width=\"1066\">0-150\u00b13% que muestra una precisi\u00f3n de 0,1%, sensor de OD de Hamilton\/Mettler, Suiza. HACER acoplamiento con agitaci\u00f3n, ox\u00edgeno.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">v\u00e1lvula de muestreo<\/td>\n<td width=\"1066\">Lata esterilizaci\u00f3n por separado, manual.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Cosecha<\/td>\n<td width=\"1066\">V\u00e1lvula inferior de zona muerta cero, esterilizaci\u00f3n de latas por separado, manual<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Sistema de pesas<\/td>\n<td width=\"1066\">Mettler-Toledo, Suiza<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Presi\u00f3n<\/td>\n<td width=\"1066\">Control autom\u00e1tico, transmisor de presi\u00f3n BD Alemania o man\u00f3metro de nivel de l\u00edquido de presi\u00f3n diferencial Lambert.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Escape<\/td>\n<td width=\"1066\">Disponer de condensador antes del escape, control mediante v\u00e1lvula de diagrama\/v\u00e1lvula de control proporcional.<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Par\u00e1metros de control<\/td>\n<td width=\"1066\">Pantalla t\u00e1ctil de 10 o 15 pulgadas, PLC Siemens con par\u00e1metros de control (agitaci\u00f3n, pH, OD, temperatura, alimentaci\u00f3n, alarma, gas, etc.), an\u00e1lisis de datos, registro de datos, salida de datos, idioma (RU\/EN\/CN) y otros personalizados. funciones<\/td>\n<\/tr>\n<tr>\n<td width=\"318\">Configuraci\u00f3n opcional<\/td>\n<td width=\"1066\">Control remoto, medidor de flujo m\u00e1sico (gas de control autom\u00e1tico), calefacci\u00f3n de escape, filtro de escape, an\u00e1lisis de escape de gas (CO2), sensor de nivel, sensor de turbidez (OD), sensor de ORP, sistema de peso, sensor de celda viva (biomasa), impresi\u00f3n, Siemens Pantalla t\u00e1ctil, Doble sello mec\u00e1nico, Grupo de 4 v\u00e1lvulas para alimentaci\u00f3n, V\u00e1lvula inferior autom\u00e1tica, Certificado ASME, Certificado CSA, flujo de aire 2vvm, etc.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><strong>A System Designed to Adapt<\/strong><\/h2>\n<p>In biotechnology, your needs can change rapidly. The <strong>100 Liter mammalian cell fermenter BLBIO-100SCUC<\/strong>\u00a0offers modular options:<\/p>\n<ul>\n<li>Remote control to manage your process anywhere.<\/li>\n<li>sophisticated sensors with which to measure the density of live cell density, ORP, or turbidity.<\/li>\n<li>Exhaust gas analysis for deeper process understanding.<\/li>\n<li>Custom bottom valves or multi-feed lines of difficult processes.<\/li>\n<\/ul>\n<p>What would you do, were your process to change tomorrow and could your equipment keep up?<\/p>\n<h2><strong>Safety and Reliability First<\/strong><\/h2>\n<p>Safety features include:<\/p>\n<ul>\n<li>Zero dead zone bottom valve, eliminating residue accumulation.<\/li>\n<li>Sterilization-separable systems of manual sampling and harvest.<\/li>\n<li>Pressure sensors and safety lamps that enhance monitoring.<\/li>\n<\/ul>\n<p>So with these the system does not merely work, it works safely batch after batch.<\/p>\n<h2><strong>Applications That Go Beyond the Ordinary<\/strong><\/h2>\n<p>Where can you use the <strong>100 Liter mammalian cell fermenter BLBIO-100SCUC<\/strong>?<\/p>\n<ul>\n<li>Production of monoclonal antibodies from hybridoma cells.<\/li>\n<li>Recombinant protein drug manufacturing with CHO cells.<\/li>\n<li>Viral vaccine production through high-density culture.<\/li>\n<li>Academic research and pilot-scale testing before industrial scale-up.<\/li>\n<\/ul>\n<p>Be it expands or using new cell lines, this fermenter helps.<\/p>\n<h2><strong>Why Gentle Mixing Matters?<\/strong><\/h2>\n<p>In mammalian cells, the shear stress may damage the quality and the viability of the product. The magnetic drive mixing system provides:<\/p>\n<ul>\n<li>Smooth, low-shear mixing ideal for suspension cell cultures.<\/li>\n<li>Uniform distribution of nutrients and gases.<\/li>\n<li>Flexibility to adapt speeds as cell density changes.<\/li>\n<\/ul>\n<p>Do you struggle with low viability or inconsistent yields? A properly designed mixing system makes the difference.<\/p>\n<h2><strong>Built for Sterility and Compliance<\/strong><\/h2>\n<p>Using CIP and SIP systems: the fermenter will always be available to your next run:<\/p>\n<ul>\n<li>Automated cleaning and sterilization reduce manual work.<\/li>\n<li>Compliant design helps meet GMP requirements.<\/li>\n<li>Smooth, polished surfaces leave nowhere for contaminants to hide.<\/li>\n<\/ul>\n<p>Could automated cleaning reduce your downtime and increase output?<\/p>\n<h2><strong>User-Friendly Digital Platform<\/strong><\/h2>\n<p>Siemens control system helps more than sustaining processes:<\/p>\n<ul>\n<li>Historical curve analysis helps spot trends.<\/li>\n<li>Alarm systems alert you before problems escalate.<\/li>\n<li>Data export keeps your quality records audit-ready.<\/li>\n<\/ul>\n<p>Consider yourself having to answer questions with real-time and past data &#8211; quicker, more confident.<\/p>\n<h2><strong>External Design Details That Matter<\/strong><\/h2>\n<p>External design isn\u2019t just aesthetic:<\/p>\n<ul>\n<li>Large sight glasses provide visual confirmation of liquid levels.<\/li>\n<li>Delay-type Philips safety lamps improve visibility during operation.<\/li>\n<li>Optimized exhaust systems protect against contamination and save heat.<\/li>\n<\/ul>\n<p>Would not these be convenient features that would make your daily operation smooth and safe?<\/p>\n<h2><strong>Supporting Large-Scale Production<\/strong><\/h2>\n<p>The design isn\u2019t just for lab-scale work:<\/p>\n<ul>\n<li>It scales seamlessly to 5KL, 10KL, and beyond.<\/li>\n<li>The same core control philosophy and quality materials.<\/li>\n<li>Modular configurations keep your facility ready for tomorrow\u2019s demand.<\/li>\n<\/ul>\n<p>Ready to grow your process? This fermenter grows with you.<\/p>\n<h2><strong>The Power of Data in Your Hands<\/strong><\/h2>\n<p>Data transforms fermentation from art into science:<\/p>\n<ul>\n<li>Record all pH, all gas and temperature changes.<\/li>\n<li>Use built-in analytics to refine your next batch.<\/li>\n<li>Reduce variability and enhance consistency.<\/li>\n<\/ul>\n<p>Did you think about the possibility of better data to double your reproducibility and yields?<\/p>\n<h2><strong>Precision Meets Flexibility<\/strong><\/h2>\n<p>Every process is unique, and your fermenter should adapt:<\/p>\n<ul>\n<li>Switch between batch, fed-batch, or perfusion processes.<\/li>\n<li>Configure gas mixes dynamically.<\/li>\n<li>Adjust feeding strategies for growth and production phases.<\/li>\n<\/ul>\n<p>How much more would your team be able to do with that sort of leeway?<\/p>\n<h2><strong>Apoyo<\/strong><\/h2>\n<p><a href=\"https:\/\/fermentorchina.com\/es\/contact-us\/\"><u>Biograf\u00eda de BaiLun<\/u><\/a>\u00a0offers:<\/p>\n<ul>\n<li>Ongoing technical support.<\/li>\n<li>Customization services to match your process.<\/li>\n<\/ul>\n<p>Try not to think about purchasing equipment per se, but having a stakeholder who will wish and take care of your success.<\/p>\n<h2><strong>Sustainability in Bioprocessing<\/strong><\/h2>\n<p>The fermenter helps sustainability by:<\/p>\n<ul>\n<li>Lowering energy costs through efficient heating\/cooling.<\/li>\n<li>Minimizing product losses with better monitoring.<\/li>\n<li>Extending lifespan with robust stainless steel construction.<\/li>\n<\/ul>\n<p>How would increase sustainability of operations affect your profits?<\/p>\n<h2><strong>In Summary: Why Invest in This Fermenter?<\/strong><\/h2>\n<ul>\n<li>Robust 316L stainless steel design.<\/li>\n<li>Smart mixing for fragile mammalian cells.<\/li>\n<li>Advanced Siemens PLC with user-friendly interface.<\/li>\n<li>Flexible configurations and modular expansion.<\/li>\n<li>Proven track record in vaccine, antibody, and protein production.<\/li>\n<\/ul>\n<p>Wouldn\u2019t your process benefit from such reliability and control?<\/p>\n<h2><strong>Make Your Next Step<\/strong><\/h2>\n<p>El <strong>100 Liter mammalian cell fermenter BLBIO-100SCUC<\/strong><strong>\u00a0<\/strong>isn\u2019t just equipment; it\u2019s your partner in pushing bioprocess limits, improving yields, and ensuring consistent, reproducible results.<\/p>\n<p>Ready to elevate your cell culture process? <a href=\"https:\/\/fermentorchina.com\/es\/contact-us\/\"><u>Contacto BaiLun Biograf\u00eda<\/u><\/a>\u00a0now and find out how this fermenter meets your requirements &#8211; and get on the way to smarter, more efficient, and scalable bio manufacturing.<\/p>","protected":false},"excerpt":{"rendered":"<p>At BaiLun Bio, we know precision fermentation technology. We also understand what a modern bioprocessipurnt requires and how to build it. Today, let\u2019s explore in depth why the <strong>100 Liter mammalian cell fermenter BLBIO-100SCUC<\/strong><strong>\u00a0<\/strong>is setting a new benchmark in mammalian cell culture, and why this innovative fermenter could be exactly what your facility or research lab needs to reach its full potential.<\/p>","protected":false},"featured_media":6501,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[26],"product_tag":[],"class_list":{"0":"post-955","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-mammalian-cell-culture-bioreactor","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product\/955","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/types\/product"}],"version-history":[{"count":3,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product\/955\/revisions"}],"predecessor-version":[{"id":7240,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product\/955\/revisions\/7240"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/media\/6501"}],"wp:attachment":[{"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/media?parent=955"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product_brand?post=955"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product_cat?post=955"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/fermentorchina.com\/es\/wp-json\/wp\/v2\/product_tag?post=955"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}