{"id":3661,"date":"2024-05-29T08:14:35","date_gmt":"2024-05-29T08:14:35","guid":{"rendered":"https:\/\/fermentorchina.com\/?p=3661"},"modified":"2025-04-25T03:39:21","modified_gmt":"2025-04-25T03:39:21","slug":"biological-fermentation","status":"publish","type":"post","link":"https:\/\/fermentorchina.com\/zh\/biological-fermentation\/","title":{"rendered":"\u751f\u7269\u53d1\u9175\u53ca\u5176\u5e94\u7528"},"content":{"rendered":"

\u53d1\u9175\u4e00\u822c\u6307\u5229\u7528\u5fae\u751f\u7269\u5236\u9020\u5de5\u4e1a\u539f\u6599\u6216\u4ea7\u54c1\u7684\u8fc7\u7a0b\uff0c\u7531\u5fae\u751f\u7269\uff08\u7ec6\u83cc\u3001\u9175\u6bcd\u7b49\uff09\u3001\u6709\u673a\u7269\uff08\u4e3b\u8981\u662f\u78b3\u6c34\u5316\u5408\u7269\uff09\u3001\u57f9\u517b\u57fa\u7b49\u5728\u4e00\u5b9a\u7684\u6e29\u5ea6\u3001pH\u7b49\u6761\u4ef6\u4e0b\u8fdb\u884c\u3002<\/p>\n

01<\/strong>\u00a0<\/strong>\u751f\u7269f<\/strong>\u53d1\u9175<\/strong>\u00a0\u6280\u672f<\/strong><\/h2>\n
\"Bailun
\u767e\u4f26\u751f\u7269\u53d1\u9175\u7f50\u52a9\u529b\u75ab\u82d7\u751f\u4ea7\u5de5\u827a<\/a><\/figcaption><\/figure>\n

\u53d1\u9175\u662f\u4eba\u7c7b\u6700\u65e9\u63a5\u89e6\u7684\u751f\u5316\u53cd\u5e94\uff0c\u917f\u9152\u3001\u5236\u9171\u3001\u5236\u918b\u7b49\u90fd\u662f\u6700\u65e9\u7684\u53d1\u9175\u5de5\u827a\u3002\u73b0\u4ee3\u53d1\u9175\u6280\u672f\u57fa\u4e8e\u591a\u5b66\u79d1\u4ea4\u53c9\uff0c\u5229\u7528\u5de5\u4e1a\u53d1\u9175\u8fdb\u884c\u5927\u89c4\u6a21\u7269\u8d28\u52a0\u5de5\u751f\u4ea7\uff0c\u6280\u672f\u5e94\u7528\u9886\u57df\u5df2\u4e0d\u518d\u5c40\u9650\u4e8e\u98df\u54c1\u996e\u6599\uff0c\u5ef6\u4f38\u81f3\u533b\u836f\u3001\u5316\u5986\u54c1\u7b49\u9886\u57df\u3002<\/p>\n

\u53d1\u9175\u6280\u672f\u539f\u7406<\/b><\/strong><\/p>\n

The principle of biological fermentation\u00a0mainly involves the metabolic process of microorganisms. Under suitable environmental conditions, microorganisms convert substrates into target products through enzyme-catalyzed reactions on substrates.<\/p>\n

The metabolic process of microorganisms includes two modes: aerobic respiration and anaerobic fermentation. Aerobic respiration refers to the complete oxidation of substrates by microorganisms in the presence of oxygen to produce energy and carbon dioxide. Anaerobic fermentation refers to the partial oxidation of substrates by microorganisms in the absence of oxygen or insufficient oxygen to produce products such as lactic acid, alcohol, acid, and gas.<\/p>\n

\u5206\u7c7b <\/b><\/strong>\u751f\u7269<\/b><\/strong>\u00a0<\/b><\/strong>\u53d1\u9175<\/b><\/strong>\u00a0\u6280\u672f<\/b><\/strong><\/p>\n

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\u4f18\u70b9 <\/b><\/strong>\u751f\u7269<\/b><\/strong>\u00a0<\/b><\/strong>\u53d1\u9175 <\/b><\/strong>\u6280\u672f<\/b><\/strong><\/p>\n

\u751f\u7269\u53d1\u9175\u6280\u672f\u76f8\u8f83\u4e8e\u5316\u5b66\u65b9\u6cd5\u5177\u6709\u53ef\u63a7\u6027\u597d\u3001\u5b89\u5168\u6027\u9ad8\u3001\u8282\u80fd\u3001\u526f\u4ea7\u7269\u5c11\u3001\u73af\u5883\u6c61\u67d3\u5c0f\u7b49\u4f18\u70b9\uff0c\u53e6\u5916\u5fae\u751f\u7269\u7684\u53ef\u5206\u89e3\u6027\u53ef\u4f7f\u7279\u6b8a\u7ed3\u6784\u7684\u751f\u7269\u5408\u6210\u4fdd\u6301\u9ad8\u5ea6\u5747\u4e00\u6027\uff0c\u4fdd\u8bc1\u4ea7\u54c1\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002<\/p>\n

\u5f53\u524d\u7814\u53d1\u70ed\u70b9<\/b><\/strong><\/p>\n

\u5982\u4eca\uff0c\u53d1\u9175\u6280\u672f\u5df2\u6210\u4e3a\u5316\u5986\u54c1\u9886\u57df\u7684\u5e94\u7528\u65b9\u5411\u548c\u7814\u53d1\u70ed\u70b9\u3002\u4f8b\u5982SK-II\u9b54\u529b\u6c34\u6dfb\u52a0\u534a\u4e73\u7cd6\u53d1\u9175\u4ea7\u7269\u6ee4\u6db2\uff0c\u5170\u853b\u5c0f\u9ed1\u74f6\u3001\u96c5\u8bd7\u5170\u9edb\u5c0f\u68d5\u74f6\u6dfb\u52a0\u53cc\u6b67\u9175\u6bcd\u53d1\u9175\u4ea7\u7269\u88c2\u89e3\u6db2\u3002\u8d8a\u6765\u8d8a\u591a\u7684\u54c1\u724c\u548c\u4f01\u4e1a\u5f00\u59cb\u5c06\u751f\u7269\u53d1\u9175\u6280\u672f\u8fd0\u7528\u5230\u4ea7\u54c1\u7ec8\u7aef\uff0c\u4e0d\u65ad\u63d0\u5347\u5316\u5986\u54c1\u7684\u5b89\u5168\u6027\u548c\u529f\u6548\u6027\u3002<\/p>\n

02<\/b><\/strong>\u00a0<\/b><\/strong>\u5e94\u7528 <\/b><\/strong>\u751f\u7269<\/b><\/strong>\u53d1\u9175<\/b><\/strong>\u00a0\u5316\u5986\u54c1\u6280\u672f<\/b><\/strong><\/h2>\n

\u76ee\u524d\u751f\u7269\u53d1\u9175\u6280\u672f\u5728\u5316\u5986\u54c1\u4e2d\u7684\u5e94\u7528\u4e3b\u8981\u5206\u4e3a\uff1a\u771f\u83cc\u53d1\u9175\u3001\u7ec6\u83cc\u53d1\u9175\u548c\u539f\u751f\u751f\u7269\u53d1\u9175\uff0c\u5176\u4e2d\u771f\u83cc\u53d1\u9175\u53c8\u5305\u62ec\uff1a\u9175\u6bcd\u83cc\u53d1\u9175\u3001\u836f\u7528\u771f\u83cc\u53d1\u9175\u548c\u6d77\u6d0b\u771f\u83cc\u53d1\u9175\u3002<\/p>\n

\"Biological
Biological Fermentation<\/figcaption><\/figure>\n

\uff081\uff09<\/b><\/strong>\u771f\u83cc\u53d1\u9175<\/b><\/strong><\/p>\n

\u9175\u6bcd\u53d1\u9175<\/p>\n

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\u836f\u7528\u771f\u83cc\u53d1\u9175<\/p>\n

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\"fungal
fungal fermentation<\/figcaption><\/figure>\n

\u6d77\u6d0b\u771f\u83cc\u53d1\u9175<\/p>\n

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\uff082\uff09<\/b><\/strong>\u7ec6\u83cc\u53d1\u9175<\/b><\/strong><\/p>\n

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\uff083\uff09<\/b><\/strong>\u539f\u751f\u751f\u7269\u53d1\u9175<\/b><\/strong><\/p>\n

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\"Factors
Factors affecting the scale-up of bio-fermentation processes<\/figcaption><\/figure>\n
    \n
  1. \u8d28\u91cf\u4f20\u9012\u548c\u6df7\u5408<\/li>\n<\/ol>\n

    The mass transfer process is the process of material transfer. In the biological fermentation\u00a0process, the mass transfer activity is carried out simultaneously with the biological reaction. The main mass transfer processes are divided into gas-liquid absorption and liquid mass transfer.<\/p>\n

    Good mass transfer can ensure the necessary oxygen, nutrients and metabolites for the culture and development of microorganisms and cells. The volume dissolved oxygen coefficient is the most important factor affecting mass transfer, but due to the complex flow field in the biological fermentation\u00a0tank and the many influencing factors, the volume dissolved oxygen coefficient analysis is more difficult.<\/p>\n

    Another key parameter that directly affects the process scale-up of the biological fermentation\u00a0tank is the mixing process. Common biological fermentation\u00a0reaction mixing includes liquid-liquid mixing, solid-liquid mixing, gas-liquid mixing and gas-liquid-solid three-phase mixing.<\/p>\n

    Since the increase in the volume of the fermentation tank and the increase in fermentation products and raw materials directly lead to uneven mixing in the tank, scientifically increasing the mixing of various substances in the fermentation tank can improve the efficiency of biological fermentation.<\/p>\n

      \n
    1. \u526a\u5207<\/li>\n<\/ol>\n

      The traditional view is that increasing the stirring rate of the bio-fermentation\u00a0tank can enhance the mass transfer and mixing of the fermentation process. However, with in-depth research, it is found that excessive shear force on the bio-fermentation\u00a0target will damage microorganisms and cells.<\/p>\n

      For example, in the microbial fermentation system, excessive shear force will damage the growth of bacteria; too low shear force is not conducive to bubble breakage and affects the efficiency of air transmission.<\/p>\n

      \u5982\u4f55\u79d1\u5b66\u5730\u63d0\u9ad8\u53d1\u9175\u7f50\u5185\u5404\u79cd\u7269\u8d28\u7684\u6df7\u5408\u5ea6\u4ee5\u53ca\u63a7\u5236\u526a\u5207\u5e94\u529b\u5728\u5fae\u751f\u7269\u548c\u7ec6\u80de\u53ef\u63a5\u53d7\u7684\u8303\u56f4\u5185\u662f\u53d1\u9175\u653e\u5927\u8fc7\u7a0b\u4e2d\u7684\u91cd\u8981\u56e0\u7d20\u3002<\/p>\n

        \n
      1. \u4f20\u64ad\u70ed\u91cf<\/li>\n<\/ol>\n

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          \n
        1. \u5176\u4ed6\u56e0\u7d20<\/li>\n<\/ol>\n

          \u751f\u7269\u53d1\u9175\u7f50\u653e\u5927\u8fc7\u7a0b\u4e2d\u8fd8\u6709\u5176\u4ed6\u56e0\u7d20\u4f1a\u5f71\u54cd\u53d1\u9175\u8fc7\u7a0b\uff0c\u4f8b\u5982\u751f\u7269\u53d1\u9175\u8865\u6c14\u3001\u8865\u6599\u901f\u5ea6\u4ee5\u53ca\u8fdb\u6599\u53e3\u7684\u8bbe\u7f6e\u7b49\u53c2\u6570\u90fd\u4f1a\u5f71\u54cd\u53d1\u9175\u8fc7\u7a0b\u3002<\/p>\n

          \u8054\u7cfb\u6211\u4eec\uff1a<\/b><\/strong><\/p>\n

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          Fermentation generally refers to the process of using microorganisms to manufacture industrial raw materials or products. It is carried out by microorganisms (bacteria, yeast, etc.), organic matter (mainly carbohydrates), culture medium, etc. under certain conditions such as temperature and pH. 01\u00a0Bio-fermentation\u00a0technology Fermentation is the earliest biochemical reaction that humans came into contact with. Winemaking, sauce […]<\/p>\n","protected":false},"author":1,"featured_media":3664,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3661","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bailun"],"_links":{"self":[{"href":"https:\/\/fermentorchina.com\/zh\/wp-json\/wp\/v2\/posts\/3661","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fermentorchina.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/fermentorchina.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/fermentorchina.com\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/fermentorchina.com\/zh\/wp-json\/wp\/v2\/comments?post=3661"}],"version-history":[{"count":4,"href":"https:\/\/fermentorchina.com\/zh\/wp-json\/wp\/v2\/posts\/3661\/revisions"}],"predecessor-version":[{"id":5449,"href":"https:\/\/fermentorchina.com\/zh\/wp-json\/wp\/v2\/posts\/3661\/revisions\/5449"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fermentorchina.com\/zh\/wp-json\/wp\/v2\/media\/3664"}],"wp:attachment":[{"href":"https:\/\/fermentorchina.com\/zh\/wp-json\/wp\/v2\/media?parent=3661"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fermentorchina.com\/zh\/wp-json\/wp\/v2\/categories?post=3661"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fermentorchina.com\/zh\/wp-json\/wp\/v2\/tags?post=3661"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}