{"id":7021,"date":"2025-10-15T05:52:30","date_gmt":"2025-10-15T05:52:30","guid":{"rendered":"https:\/\/fermentorchina.com\/?p=7021"},"modified":"2026-03-05T08:59:20","modified_gmt":"2026-03-05T08:59:20","slug":"gut-skin-link-microbes-show-in-skin-health","status":"publish","type":"post","link":"https:\/\/fermentorchina.com\/zh\/gut-skin-link-microbes-show-in-skin-health\/","title":{"rendered":"\u80a0-\u76ae\u80a4\u8f74\uff1a\u5fae\u751f\u7269\u5931\u8861\u7684\u5916\u90e8\u4fe1\u53f7"},"content":{"rendered":"

Your skin can show signs of how healthy your intestine\u00a0is. The enteric\u00a0and skin are connected. They work together through things like enteric\u00a0bacteria, the immune system, and hormones. This is called the \u201cgut\u2013skin axis.\u201d When gut bacteria are out of balance, it can lead to skin problems. These may include acne, psoriasis, or atopic dermatitis.<\/p>\n

\"Gut\"<\/p>\n

Some enteric\u00a0bacteria break down fiber from food. This makes short-chain fatty acids (SCFAs) like butyrate. These SCFAs help reduce inflammation. For example, butyrate helps certain immune cells called Treg cells. These cells help calm the body\u2019s reaction and stop skin problems like atopic dermatitis from getting worse.<\/p>\n

But some harmful bacteria, like gram-negative bacteria, make something called lipopolysaccharides (LPS). LPS can get into the blood. After that, it can reach the skin and make inflammation worse. This can lead to more acne or psoriasis.<\/p>\n

Studies show that people with acne often have less Bacteroides and more Proteobacteria in their enteric. Taking Lactobacillus and Bifidobacterium for 12 weeks can help. It can make acne 40% less severe.<\/p>\n

Children with atopic dermatitis often don\u2019t have enough Bifidobacteria in their gut. If babies take Lactobacillus rhamnosus GG, they may have a 20% lower chance of getting this skin problem later.<\/p>\n

Gut\u2013Endocrine Axis: The Regulatory Center of Metabolic Balance <\/strong><\/h2>\n

The enteric\u00a0sends signals to other organs in the body. It can talk to the pancreas and thyroid. This is known as the \u201cgut\u2013endocrine axis.\u201d Gut bacteria make things like SCFAs and bile acids. These can affect how the body uses insulin. They can also change hormone levels and body weight.<\/p>\n

People who are overweight often have more Firmicutes and fewer Bacteroidetes. This type of bacteria mix helps the body take in more energy from food.Conversely, a high-fiber diet that increases SCFA production can lead to a 5 kg weight reduction and a 4 cm decrease in waist circumference.<\/p>\n

Type 2 diabetes patients often lack butyrate-producing bacteria. Supplementing Akkermansia for three months can improve insulin sensitivity by 30%.<\/p>\n

Polycystic ovary syndrome (PCOS) is also linked to\u00a0intestine dysbiosis. A decrease in Bacteroidetes is closely associated with hyperandrogenism. Probiotic supplementation can lower testosterone levels by 20% and help regulate menstrual cycles. Modulating the\u00a0intestine microbiome is becoming a new intervention target for metabolic diseases.<\/p>\n

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\"Gut\"<\/p>\n

Gut-Brain Axis: The Invisible Hand Behind Emotion and Cognition<\/strong><\/h2>\n

Calling the intestine the \u201csecond brain\u201d is no exaggeration. The \u201cgut-brain axis\u201d connects the\u00a0intestine\u00a0and brain via the vagus nerve, microbial metabolites, and immune pathways.<\/p>\n

The intestine produces 95% of the body’s serotonin. SCFAs can cross the blood-brain barrier and promote the release of brain-derived neurotrophic factor (BDNF), improving cognition. On the flip side, a leaky intestine allows LPS into the bloodstream, which may activate microglia and trigger neuroinflammation, contributing to Alzheimer\u2019s disease.<\/p>\n

Depressed individuals often show decreased Prevotella and increased Enterococcus. Supplementing Lactobacillus plantarum PS128 for 8 weeks can reduce Hamilton Depression Rating Scale scores by 35%.<\/p>\n

Early symptoms of Parkinson\u2019s disease \u2014 like constipation \u2014 are also linked to reduced Akkermansia in the gut. Taking care of your intestine might be the key to protecting both mood and mind.<\/p>\n

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airlift-mixing-stainless-steel-bioreactor<\/figcaption><\/figure>\n

Other Gut Axes: A Coordinated Network for Whole-Body Health<\/strong><\/h2>\n

The gut\u2019s influence doesn\u2019t stop there:<\/p>\n