As the market size of biological fermentation continues to expand, fermenters are widely used in bioengineering, pharmaceuticals and other fields. Fermenter manufacturing technology is also increasingly advanced and has entered an automated development stage, meeting various fermentation needs and improving fermentation quality.
Fully automatic Fermenter
A fermenter is a device system that provides an adaptive reaction environment for living cells or enzymes to undergo cell proliferation or production, which is a type of bioreactor. The production of fermenters needs to be structurally tight, able to withstand repeated steam sterilization, have smooth inner walls, and good corrosion resistance to reduce the impact of metal ions on biological reactions.
With the implementation of the new version of GMP, the country has put forward higher requirements for drug quality, and sterility and pollution-free have become the basic standards for pharmaceuticals. Therefore, fully automatic fermentation tanks have emerged.
The application of automation technology makes the sealing of fermenter stronger, which can better achieve safety, hygiene, and pollution-free, achieve in place high-temperature sterilization, and better comply with national GMP hygiene standards.
The fully automatic fermenter can be equipped with heating jackets according to process requirements, and the heating methods include electric heating, steam heating, thermal oil heating, and far-infrared heating stirring tank. A nozzle can also be added at the top of the mixing tank to atomize the mixing process. The motor can be equipped with electromagnetic speed regulation or cycloidal pinwheel reducer. The mixing slurry can be mixed in various forms such as slurry type, frame type, push type, inclined blade type, etc., which are safer and more reliable to use, and the operation and maintenance are more convenient and simple.
The pharmaceutical industry can effectively reduce manual errors through the development of automation and digital technology, thereby ensuring pharmaceutical quality and compliance, and solving problems faster and more effectively. In response to the safety and health standards for pharmaceutical machinery automation, Bailun has also developed several fully automatic fermenters.
01 Automatic fermenter (CGMP compliant)
Double-end mechanical seal completely solves the problem of bacterial contamination in biological product tank culture. Various parameters such as pH, DO, temperature and speed in fermentation can be monitored by the controller, and all data and control parameters can be transmitted to the controller or computer. The structure is compact and various components can be integrated into the fermentation system.
You can choose to use the upper drive direct coupling mechanical stirring or the lower drive magnetic indirect coupling mechanical stirring method, which has a simple structure and stable operation.
02 Full–automatic metabolic flow fermenter
Stainless steel tank body, no dead corners in the tank body, spherical tank bottom head, can obtain better fluid performance and the best mixing effect. The long glass sight glass is convenient for observing the state in the tank, and the sight glass lamp is specially designed with a quick interface, which is convenient and safe to operate.
Standard pH, DO, and temperature interfaces are reserved, and the multi-valve combination design is designed for aseptic sampling and discharge ports. The tank top includes an inoculation port, a feeding port, a foam electrode interface, an exhaust condenser interface, and multiple spare ports.
The system uses a tablet computer of more than 10 inches to control or collect 17 direct parameters such as pH, DO, tank pressure, temperature, speed, air flow, exhaust O2, exhaust CO2, feed weighing, fermentation liquid volume, etc., and can calculate indirect parameters.
The pipeline valves are all made of stainless steel, and the sanitary pipeline valves for food and fermentation simplify the pipeline design and reduce the chance of contamination while achieving complete functions. The structure is reasonable and beautiful.
Bailun fully automatic metabolic flow fermenter
03 Automatic fermenter (GMP)
Based on the study of European fermenters, the automatic control of the fermenter sterilization process is realized through simple pipelines and heat exchange systems, which reduces the labor intensity of experimental personnel, has a simple structure and stable operation.
It adopts the upper drive direct coupling mechanical stirring or the lower drive magnetic indirect coupling mechanical stirring method, with simple structure and smooth operation.
The reasonable treatment of every detail of Bailun will provide more guarantee for the quality of the fermenter, and the quality of pharmaceutical products will be further guaranteed.
Nowadays, Bailun Bio is constantly strengthening technological innovation and promoting the improvement of product equipment. Bailun fully automatic fermenter has made great progress in production process and technology, and is playing a pivotal role in the application process of the biological industry.
bailun GMP automatic fermenter
About Bailun
Bailun has extensive experience in manufacturing various types of reactors and pressure vessels. It has a team of experts in the fields of bioreactors, fermentation processes, mechanical manufacturing, and automated control. Its scientific research and technological level are always at the leading domestic and world-class level, providing you with a comfortable, assured, and secure product experience.
Contact Us:
Add:6848# Liuxiang Rd., Jiading, Shanghai, China
Contact Person: Maddie
Email:[email protected]
Phone:+86-134-7276-8163 (WhatsApp)
Website: https://fermentorchina.com/
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