Introducing the 50L 5‑duplex stainless steel fermenters BLBIO‑50SJA‑5

Ready to elevate your lab’s capacity and efficiency? When every aspect of a compact powerhouse counts, 50L 5 duplex stainless steel fermenters BLBIO-50SJA-5 is the ideal fit. The product is very compact and powerful to meet up the requirements of modern bioscience workflows, including simple batch productions, advanced fed batch planning, and animal cell culturing. This fermenter system is extremely versatile due to the robust peristaltic pump set-up, intuitive color touch screen and modular duplex design. There is no more flexible and capable fermenter than this one.

Imagine running several fermentation processes in a parallel manner, each of the units priding, specifically, precision control temperature, pH, DO, stirring, and gas. Curious how this setup transforms your lab experience? Keep reading!

Modular Duplex Greatness

Two Independent Vessels, Twice the Flexibility

The system is designed in the so-called 5-duplex configuration which implies that there are 2 fermenters with the capacity of 50 L each, and there is one control station. They operate in a stand-alone center- a batch, a replicate or parallel strain testing, or continuous, as in simultaneous batch and fed-batch procedures. Imagine running two proteins or vaccine candidates side by side!

Precise, Unified Control

Both tanks are controlled by a single Siemens PLC that have a 10 or 15-inch touch screen and the task is easily achieved. Follow and digitally manipulate set points, access data trends, and alarm tracking, all led in close integration. Want to compare parameter response across runs? The versatile display makes it easy.

Compact Integration

This isn’t two tanks plastered together, it’s a purpose-engineered system with shared pumps and compact footprint. Pipes, sensors, piping, and controls are integrated. Conserve space and reduce complication in an efficiency focused lab based system.

Core Features That Matter

Intuitive Touchscreen Control

Monitor important process variables through a simple-to-see color interface such as pH, DO, temperature and stirring speed. Tuning parameters? It’s only a tap away. Data logging, SOP recall, and multi-language support (EN/CN/RU) make operation smooth and standardized.

Peristaltic Pumps: Feed, Foam, Balance

Beside every tank there are four precision peristaltic pumps that can be used to:

• Acid addition (pH control)
• Base addition (pH control)
• Antifoam dosing
• Nutrient/media feed

Everything was in real-time, and the sensors provided feedback in order to automatically adjust the processes.

Stirring Options: Top or Bottom Drive

Choose either:

• Mechanical drive with top or bottom coupling, or
• Magnetic drive (top-mounted)

Three adjustable six‑blade impellers offer mixing speeds ranging from 50–1000 rpm (mechanical) or 50–400 rpm (magnetic).

Sterility & Cleanliness

• SIP –automated Sterilize-In-Place
• CIP –Clean-In-Place via spray ball

Valves that can also be sterilized, such as harvesting, are improved to prevent dead zones

Sensor Suite

• pH: 2.00–12.00 ± 0.1 (Hamilton/Mettler)
• DO: 0–150 % ± 3 % with 0.1 % resolution (Hamilton/Mettler)
• Temperature: 5 °C–70 °C (electric or jacketed water)

All of which are coupled with automatic feedbacks through PLC.

Technical Specifications

PARAMETER	DESCRIPTION
Volumen total	5 L, 10 L, 15 L, 20 L, 30 L, 50 L, 100 L, 200 L, 500 L, 1000 L, 5KL, 50KL, 200KL etc.
Volumen de trabajo	30 % – 70 % of total
Tanque	Jacketed SS316/SS304, 0.3 MPa vessel / 0.35 MPa jacket, 0.4–0.6 µm polish, height-to-diameter ratio 1:2.2–2.5
Sistema de agitación	Mechanical (top/bottom) or magnetic (top), 3× height-adjustable six-blade paddles
Stir speed	50–1000 rpm (mechanical) / 50–400 rpm (magnetic)
Esterilización	SIP (Sterilize-In-Place), program-controlled
Limpio	CIP (Clean-In-Place) via spray ball
control de gases	Rotor meter; 1 vvm airflow
Alimentación	Automatic via peristaltic pump
Control antiespumante	Automatic via peristaltic pump
Control de temperatura	Auto-controlled; 5 °C–70 °C (electric/water jacket)
pH control	2.00–12.00 ± 0.1; acid/base dosing peristaltic pumps; Hamilton/Mettler sensors
HACER control	0–150 % ± 3 %, precision 0.1 %; Hamilton/Mettler sensors; agitation+oxygen coupling
Muestreo	Manual sampling valve, separately sterilizable
Cosecha	Zero-dead-zone bottom valve (Gemu/Bürkert, GER), separately sterilizable, manual/auto
Sistema de elevación de tapa	30–500 L systems include hydraulic lid lift; 700–1000 L use human-access port
Presión	Automatic via BD Germany pressure transmitter
Escape	Condenser + diaphragm/proportional control valve
Parámetros de control	Siemens PLC with 10″ or 15″ touchscreen, stir/pH/DO/temp/gas/feeding/alarm control, data logging, multilingual (RU/EN/CN), customization available
Optional configuration	Remote control, mass flow meter, O₂/N₂/CO₂ flow, 2 vvm gas, CO₂ exhaust analysis, level/turbidity/ORP/biomass sensors, printing, Siemens HMI, double seal, 4-valve feeding, auto discharge, ASME/CSA, batch culture, seed transfer etc.

Why Are The 50L 5 duplex stainless steel fermenters BLBIO-50SJA-5 Special?

1. Duplex Convenience

Ever wanted to compare two culture conditions side‑by‑side? Or progressively escalate volume while keeping SOP uniform? This is precisely what this duplex system allows five communal pumps, a single display, two independent un-controlled tanks.

2. All-in-One Control

No more juggling multiple units or displays. The Siemens PLC sits at the heart, each tank gets its own control “session”, but all tied to one interface. Want to export your run’s data? Download it from one system, not two.

3. Sterile and Streamlined

The stainless steel build (SS316/304) with superior polish, plus SIP/CIP, ensures no hidden corners, just quick sterilize-clean cycles. Sampling and harvesting are sterile and dead-zone free.

4. Scalable & Adaptable

Constructed to do microbial fermentation as well as sensitive animal cell culture. Want a third tank someday, or a seed-stage vessel? You may plug it into the same control cabinet or by the future you can grow your system.

Common Applications & Use Cases

Microbe fermentation -E. coli, Bacillus, yeast, fungal strains that generate enzymes, metabolites, or minute molecules

• Animal cell culture –CHO, HEK293, Vero as a source of protein, antibody or vaccine
• Fed-batch or continuous –Automation of nutrient feed and of foam control provided
• Parallel bioprocessing –Axioms parallel bioprocessing is an efficient way of optimizing the process, making comparisons between the strains and validating SOPs simultaneously
• Pilot and scale-down models –Pilot and scale-down models can help generate process data which can be scaled up or down by a factor of 50 L to 500 L or even more

How It Works?

• Setup –Load tanks with media (30–70 % fill), connect sensors and pumps
• SIP & CIP-run sterile cycle, wash when it is sterile, then move on to growth
• Inoculation-The starter culture can be added through inoculation port or aseptic sampling line
• Control-Monitor the temperature, pH level, DO and stirring in real-time
• Dose Decisions –automatic liquid dose additions of pH, DO, antifoam and nutrients
• Run Time –Trend touchscreen, alarm on the deviations
• Sampling & Harvest-Harvest/take biomass through sterile valve/hose
• Cleanup & Next Run –clean CIP rinse tanks and make them ready to go in next batch

Why Choose This Fermenter?

• Duplex Advantage –Parallel workflows, simultaneous experiments, scaling-down risk
• Integrated Control —A unified parameter deployment realized by a single system and two tanks
• Clean footprint labs —Pipelines and lab design are clean and efficient, and sterile Piradio
• Premium Hardware –German sensors, Swiss probes, Siemens automation
• Scalable Future-When more tanks / sensors are arrived add them in the future without replacing sensor cabinet

Engaging Lab Scenarios: Is This You?

Biotech R&D Teams

Fine-tuning vaccine yield? Actively compare two mechanisms of the strategy of supply and control simultaneously, that is, of one and the same order, with differing variables.

Academic Research Labs

Run microbial and cell culture in one system. Perfect for studies requiring both.

Startups & CDMOs

Looking to get two 50 L vessels that have little footprint, high impact? Two runs, one machine, cost-effective and efficient.

SOP Validation & Audits

Run replicate batches to validate SOP consistency. Every sensor’s traceable and exportable for audit trails.

Take Action Today

Need a quote? We can then make up a custom setup with optional sensors such as mass flow, biomass, turbidity, or ORP. Whether you’re scaling a strain, running cell culture, optimizing feeds, or validating your SOP, this system elevates control, reproducibility, and efficiency, all with just the right footprint.

What is restraining you to upgrade your lab that increases throughput, reliability and data integrity? The 50L 5 duplex stainless steel fermenters BLBIO-50SJA-5 is ready for your next breakthrough, let’s talk!

Preguntas frecuentes

1. Can I run different processes in each tank?

A: Absolutely. Parameters can be run separately on each of the 50 L fermenters within the duplex, which is perfect in case of process comparison, replicates, or multi strains.

1. What stirring configurations are available?

A: Select between direct-drive mechanical shaft (top or bottom coupled) or magnetic drive with three height-adjustable six-blade impellers. Speeds range 50–1000 rpm.

1. Is the system CIP/SIP compliant?

A: Yes. Sterilize-in-place and clean-in-place systems are fully automated – so you can go from run to run without ever taking them apart.

1. Are sampling and harvest sterile?

A: Yes, sampling valves are autoclave-compatible, and bottom harvest valves (Gemu/Bürkert) are zero-dead-zone and can be sterilized individually.

1. How do I monitor data and exports?

A: The Siemens touchscreen gives trend graphs and data logging. Export capabilities (USB/RS232/Ethernet) integrate with your LIMS or process documentation system.