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Fermentation generally refers to the process of using microorganisms to manufacture industrial raw materials or products. It is carried out by microorganisms (bacteria, yeast, etc.), organic matter (mainly carbohydrates), culture medium, etc. under certain conditions such as temperature and pH. 01 Bio-fermentation technology Fermentation is the earliest biochemical reaction that humans came into contact with. Winemaking, sauce

Introduction to Microbial Fermentation Microbial fermentation refers to the process of using microorganisms to convert raw materials into products required by humans through specific metabolic pathways under suitable conditions. The level of microbial fermentation production mainly depends on the genetic characteristics and cultivation conditions of the strains themselves. The application scope of fermentation engineering includes

Sensors are an important part of bioreactor process control, controlling temperature, pH, dissolved oxygen, and stirring speed. As bioreactor design and control advances, so do the requirements for sensing technology. For example, single-use bioreactors (SUB) are becoming more popular, and single-use solutions for pH and DO are also being introduced. However, most of the sensors

Tetanus is an extremely serious acute infectious diseases caused by Clostridium tetanus invading the human body through skin or mucosal wounds, growing and reproducing locally in the wounds and producing toxins. After entering the human body, Clostridium tetanus produces exotoxins with spasmodic and hemolytic toxicity, which are extremely toxic and can cause functional changes in

A bioreactor is a type of equipment widely used in life sciences and engineering, which can be used to develop and produce various biological products. With the continuous development of biotechnology, the scale and automation of bioreactors are also increasing. In this article, we will explore the technologies associated with the scale-up and automation control

Mammalian cells have been used as carriers for the production of therapeutic proteins for decades. Therapeutic proteins are widely used in the diagnosis and treatment of diseases, forming a huge market. The global biopharmaceutical market was valued at USD 237.2 billion in 2018 and is expected to reach USD 389 billion by 2024, registering a

Domestic science and technology and production technology are changing with each passing day, and the sealing requirements of the biopharmaceutical industry have become more and more stringent. The coordination of the reaction tank and the mixing device is an important part of the entire production process, so the CGMP (Dynamic Drug Production Management Specifications) requirements

“Synthetic life, design life” is an important mission of synthetic biology and biomanufacturing, through on-demand design and chemical reconstruction of artificial genomes, to achieve the precise construction of artificial cell factories. At present, cell factories are faced with bottlenecks such as complex metabolic networks, lack of rational design, high cost of trial and error, and