100 Liter Stainless Steel Bottom Mechanically Agitated Fermenter BLBIO-100SJB

Designed to Outperform: Why Choose Bottom Mechanically Agitated Fermenter?

• All stainless-steel 316L durable, polished stainless steel with hygienic design.
• Bottom mechanical stirring- provides stable and even mixing, which is ideal in a variety of cultures.
• Completely automated control system powered with Siemens PLC and working on the touchscreen.
• Clean-in-place (CIP) & sterilize-in-place (SIP), save time, reduce contamination risk.
• Adaptable applications, Fits well with bacteria, yeast, fungus, mammalian and plant cells, vaccines, enzymes and so on.

Have you ever experienced any process challenge of inconsistent temperature or oxygen flow? The design of diversion and bottom stirring on this fermenter makes it uniform within the vessel.

Fermenter Description: What Sets the 100 Liter Stainless Steel Bottom Mechanically Agitated Fermenter Apart?

El 100 Liter Stainless Steel Bottom Mechanically Agitated Fermenter BLBIO-100SJB isn’t just about volume. With its superior capabilities, it is famous among biotechnology and pharmacology specialists:

• Corrosion resistant and simple to clean, all stainless steel 316L tank body.
• Steam sterilized: is seen to last longer and offer superior protection through its double mechanical seal.
• Special sampling & discharging valves for aseptic processes.
• Large viewing glass for real-time observation.
• Integrated ports for temperature, pH, DO sensors, and feeding/inoculation.
• Optimized diversion design for better temperature and nutrient distribution.
• Air distributor and precision rotameter for accurate gas flow.

All welds are done to be strong, neat and fine polished to 0.4-0.6um – the epitome of beauty and utility.

Fermenter Technical Specifications

Every performance and reliability that you require, at one glance:

Bottom Mechanically Agitated Fermenter Parámetros técnicos:

Parámetro	Ddescripción
Volumen total	5L, 10L, 15L, 20L, 30L, 50L, 100L, 200L, 500L, 1000L, 5KL, 50KL, 200KL, etc.
Volumen de trabajo	30%~70%
Tanque	Tanque con camisa, fabricado con SS316 y SS304, presión de diseño del tanque de 0,3 Mpa, presión de diseño de la camisa de 0,35 Mpa, pulido de 0,4 a 0,6 um, relación de diámetro y altura de 1:2,2 a 2,5
Sistema de agitación	Accionamiento mecánico en la parte superior/inferior o accionamiento magnético en la parte superior, paleta de seis hojas ajustable en altura de 3 piezas Velocidad de agitación: 50~1000rpm/50-400rpm
Esterilización	Esterilizar en el lugar (SIP), control automático por programa
Limpio	Limpieza in situ (CIP) mediante bola rociadora
control de gases	Control por medidor de rotor, caudal de aire 1 vvm
Alimentación	Alimentación automática mediante bomba peristáltica.
Control antiespumante	Agregue antiespumante automáticamente mediante bomba peristáltica
Control de temperatura	Autocontrol, rango de calefacción eléctrica: la fuente de agua agrega 5 ℃ a 70 ℃
control de ph	PH 2,00-12,00±0,1, control automático de adición de ácido/base mediante bomba peristáltica, sensor de pH de Hamilton/Mettler, Suiza.
hacer control	0-150±3% que muestra una precisión de 0,1%, sensor de OD de Hamilton/Mettler, Suiza. HACER acoplamiento con agitación, oxígeno.
Muestreo	Válvula de muestreo, esterilización de botes por separado, manual.
Cosecha	Válvula inferior de zona muerta cero (Gemu/Burket, Alemania), esterilización de latas por separado, manual/automática
Sistema de elevación de tapa	30L-500L tienen sistema de elevación de tapa, 700-1000L tienen agujero humano.
Presión	Control automático, transmisor de presión BD Alemania
Escape	Disponer de condensador antes del escape, control mediante válvula de diagrama/válvula de control proporcional.
Parámetros de control	Pantalla táctil de 10 o 15 pulgadas, PLC Siemens con parámetros de control (agitación, pH, OD, temperatura, alimentación, alarma, gas, etc.), análisis de datos, registro de datos, salida de datos, idioma (RU/EN/CN) y otros personalizados. funciones
Configuración opcional	Control remoto, medidor de flujo másico (gas de control automático), O2/N2/CO2, flujo de gas 2vvm, análisis de escape de gas (CO2), sensor de nivel, sensor de turbidez (OD), sensor de ORP, sistema de peso, sensor de celda viva (biomasa) , Impresión, Pantalla táctil Siemens, Doble sello mecánico, Grupo de 4 válvulas para alimentación, Descarga automática de válvula inferior, Certificado ASME, Certificado CSA, Cultivo por lotes, Transferencia de semillas, etc.

Smart Control with Siemens PLC

Imagine having every critical parameter at your fingertips.

• This fermenter incorporates a German Siemens S7-200 type PLC with a 10-inch LCD touchscreen:
• View real-time data (pH, DO, temp, stirring speed, gas flow)
• Automatic process control
• Historical data logging & export
• User-friendly interface in English, Chinese, and more
• Menu-driven navigation for fast learning curve

Tired of manual adjustments? Under automated control you concentrate on the results rather than on continuous watching.

Fermenter Applications

El 100 Liter Stainless Steel Bottom Mechanically Agitated Fermenter BLBIO-100SJB can be used:

Animal vaccine production:

• Avian influenza, PRRS, foot-and-mouth, rabies, mink vaccines
• DTP, diphtheria, tetanus

Human vaccines:

Meningitis, pneumonia IV, hepatitis B, diphtheria, tetanus

Other Fermentation Processes:

• Bacterial, fungal & yeast cultures
• Mammalian cell lines (CHO, HEK293)
• Plant cells, algae, enzymes, proteins
• Antibiotics, food additives

It can be used successfully on R&D to pilot scale due to its perfect mixture and temperature control.

Bottom Mechanical Stirring: Why It Matters

Bottom mechanical stirring ensures:

• Even distribution of heat and nutrients
• Reduced vortexing compared to top drives
• Better control for shear-sensitive organisms
• Stability at varying volumes

Ever wondered if bottom stirring fits your process? In cases in which your product will work best under even conditions, bottom stirring can be of great benefit.

 Gas & Ventilation: Deep Ventilation Done Right

• Integrated air distributor spreads gas evenly.
• Rotameter allows fine-tuned manual gas adjustment.
• Sterilizing filters (Dominic/Shanghai Yiming) with 0.2μm pore prevent contamination.
• Steam sterilized condensate cooling keeps seals lubricated and safe.
• Outcome: improved oxygen transfers rate, safer usage and a longer equipment functioning life.

Engineered for Hygiene & Durability

• All internal welds are smooth & neat.
• Polished to Ra ≤ 0.4–0.6μm, reducing contamination risk.
• Steam sterilization with automatic temperature control.
• 2-mechanical seal cooled & lubricated steam condensate.

The design reduces the time of cleaning and maintains low batch-to-batch contamination.

Process Optimization & Scalability

El 100 Liter Stainless Steel Bottom Mechanically Agitated Fermenter BLBIO-100SJB is a laboratory-scale up unit:

• Equal geometry and mixing at various volumes, processes can be easily validated.
• Data logging helps refine your protocols over time.
• Remote access options let you monitor anywhere.

Ready to move from lab to pilot? This one is your over-bridge that builds 5L to 200KL systems, each one as detailed as the other.

Optional Configurations & Custom Features

Customize your fermenter to match your exact needs:

• Mass flow meter for automatic gas mixing
• CO₂ exhaust gas analysis
• Turbidity, biomass & ORP sensors
• Automatic bottom valve discharge
• Batch culture & seed transfer modes
• Double mechanical seals & 4-valve feeding groups
• Certificates: ASME, CSA for Regulatory Compliance

Such adaptability maintains your investment up to date as your process changes in the future.

 Sustainable Bioprocessing Benefits

• Lower water & cleaning agent consumption with CIP/SIP.
• Energy-efficient design.
• High durability reduces replacement needs.

By investing on quality equipment, the lifecycle cost decreases and the unscheduled startup is minimized.

Intelligent Design Features

• Large viewing window & internal light.
• Liquid level interfaces and multiple spare ports.
• Compact footprint with lid lift system.
• Zero dead zone valve for full drainage.

All of this makes your work efficient and your data reliable.

Real-World Results: What You Can Produce?

• Recombinant proteins & enzymes
• Vaccines (viral & bacterial)
• Cell culture-based products
• Algal biomass
• Organic acids & amino acids
• Antibiotics & therapeutic proteins

The fermenter is flexible regardless of whether you need food, pharma, or research products.

Quick Recap: Why It Stands Out

• Robust stainless steel build
• Bottom mechanical stirring for stable, even mixing
• Automated Siemens PLC control
• CIP & SIP for top hygiene
• Flexible volumes and applications
• Global sensor & valve brands (Hamilton, Gemu, BD, etc.)

100 Liter Stainless Steel Bottom Mechanically Agitated Fermenter BLBIO-100SJB is not only just a machine, it is a heart of your bioprocess lab.

Ready to Upgrade Your Fermentation?

Think even quicker scale-up, reduced contamination threat and wiser management of each batch.

Become familiar with Biografía de BaiLun, visit the company at the given contact, call today to discuss or have a quote tailored to your own requirements.