Discover the Stainless steel fermenter 100 liter BLBIO-100SJA

 

Do you want to make your R&D and pilot-scale operations high performance-high reliable? Here comes a uniquely designed, scrupulously engineered, precision, versatile, and repeatable 100 L bioreactor Stainless fermenter 100 Liter BLBIO-100SJA! Whether it be vaccine R&D or enzyme manufacturing, microbial fermentations or animal cell culture, through this system you can get in on the highest level of bioprocessing.

But what sets this fermenter apart from others? and how does it make your laboratory efficiency and data control so high? Let’s dive in!

Strengths of The Stainless Steel Fermenter 100 Liter BLBIO-100SJA

1. Premium Stainless Steel Construction

The fermenter consists of a complete SS316L tank and mirror finish polished interior of 0.4 0.6 0. This fermenter has smooth surfaces, no dead zones and easy CIP cleaning. Need flawless sterility in vaccine production or biologic manufacturing? This tank is built for it.

2. Flexible Port Configuration & Safety Features

This design is designed with a large-angle observation glass, 12⏃V safety light, temperature, PH, DO interface, and inoculation, feeding, and spare port so that various processes can be supported. Want robust sterilizable sampling and harvest valves? Look no further.

3. Efficient Gas-Air Management

Featuring one-way deep ventilation, adjustable gas flow via rotameter, internal sparger, and a 0.2 µm sterilizing filter (Dominic or Yiming) to prevent backflow. Answer: uniform oxygen distribution with maximum safety.

4. Precision Automation via Siemens Control

This was driven by a Siemens S7-200 PLC using a 10 color touch screen with complete English menu. Available in real time are stirring speed, temperature, pH, DO monitoring, data logging capabilities, and monitored and analyzed (historically) by the user.

5. Versatile Process Capabilities

Batch, fed-batch through to animal cell culture, this bioreactor is made well. Scalable, flexible and reliable-an excellent choice in the application of vaccine, enzyme and cell therapies.

Technical Parameters at-a-Glance

ПАРАМЕТР	ОПИСАНИЕ
Общий объем	5 л, 10 л, 15 л, 20 л, 30 л, 50 л, 100 л, 200 л, 500 л, 1000 л, 5КЛ, 50КЛ, 200КЛ и т. д.
Рабочий объем	30 % – 70 % of total volume
Бак	Jacketed SS316/SS304; tank pressure 0.3 MPa; jacket 0.35 MPa; interior polish 0.4–0.6 µm; H:D ratio 1:2.2–2.5
Система перемешивания	Mechanical drive (top/bottom) or magnetic drive (top); 3 height-adjustable six-blade paddles
Скорость перемешивания	50–1000 об/мин (механический) / 50–400 об/мин (магнитный)
Стерилизация	SIP – Sterilize-In-Place, fully automated
Чистый	CIP – Clean-In-Place via spray ball
Газ-контроль	Rotameter-controlled airflow (standard 1 vvm)
Кормление	Автоматически через перистальтический насос
Контроль пенообразования	Автоматически через перистальтический насос
Контроль температуры	Auto-regulated; 5 °C–70 °C using jacket (electric/water source)
контроль pH	2.00–12.00 ± 0.1; acid/base dosing via peristaltic pump; Hamilton/Mettler sensor
ДЕЛАТЬ контроль	0–150 % ± 3 % with 0.1 % resolution; Hamilton/Mettler sensor (agitation + oxygen coupling)
Выборка	Manual, sterilizable sampling valve
Урожай	Zero-dead-zone bottom valve (Gemu/Bürkert, Germany), sterilizable, manual or automatic
Система подъема крышки	30–500 L units utilize hydraulic lid lifts
Pressure control	Automated via BD Germany pressure transmitter
Exhaust system	Condenser with diaphragm or proportional control valve
Параметры управления	Siemens PLC, 10″ or 15″ touchscreen; monitoring and control over stirring, pH, DO, temperature, feeding, gas, alarms, data; RU/EN/CN interface, exportable
Optional configurations	Remote control, mass flow meter, O₂/N₂/CO₂ blends (up to 2 vvm), CO₂ analysis, level/turbidity/ORP/biomass sensors, printing, double seals, ASME/CSA, batch options

What Operators Love About This Fermenter?

1. Safety, Hygiene & Durability

It is built in stainless steel with pressure vessels and jacket that guarantee strength. Port and valve systems are sterilizable maintaining a septicity and repeatability of processes. Safety exhaust condenser avoids aerosol risks.

2. Comprehensive Automation

The touchscreen interface combined with Siemens PLC allows controlling all parametric in a real-time mode. Ideal for long-term batch runs or tight SOP adherence. Want data trends for regulatory audits? It’s built in.

3. Adaptability for Growth

Scale media from 30–70 % working volume easily. Having the option of heating jackets electronically- these are flexible to yeast, microbe or mammalian cell culture. Planning to scale to 200 L? The design supports it.

4. Data-Driven Decisions

Trend curves, data exports (USB/Ethernet), alarms, and logs make cross-run analysis and process optimization easy. Want to compare yields across control algorithms? The system helps you do it.

5. Economical with Precision

SIP/CIP conserves space and resources as well as labors time through coordinated controlling. Automated pumps (acid, base, foam, media) reduce manual intervention, and human error.

What Applications Does It Serve?

Stainless steel fermenter 100 Liter BLBIO-100SJA is suitable to the industries and research sectors such as:

• Animal vaccine production:avian flu, porcine reproductive and respiratory syndrome (PRRS), foot and mouth disease (FMD), rabies, mink, diphtheria-tetanus and diphtheria vaccines
• Human vaccinations:meningitis, pneumonia IV, hepatitis B, diphtheria and tetanus
• Microbial culture:bacteria, fungi, yeast, to form enzymes, antibiotics, organic acid
• Mammalian cell culture:(CHO, HEK293, Vero, biologic cell cultures and viral vectors)
• Plant cell, algae systems:secondary metabolites, bioactive compounds
• Protein and additive synthesis:industrial enzymes, nutritional supplements

If you’re scaling from shake flasks to pilot runs or producing validation batches, the Stainless steel fermenter 100 Liter BLBIO-100SJA delivers the control and quality you need.

Detailed Breakdown: Built for Performance

1. Tank & Jacket System

• SS316/304 build for sterility and corrosion resistance
• Pressure-rated design for controlled heat exchange
• Smooth welds and clean hygienic design suitable to full CIP compatibility
• Glass window with safety lighting enables remote monitoring

2. Stirring & Agitation

• Mechanical/magnetic drive formats, use shear sensitivity to decide which one to elect
• Three adjustable six-blade impellers for optimal mixing
• Seed RPM: includes sensitive cell cultures to fast growing microbial cultures

3. Gassing & Aeration

• One-way deep ventilation with internal diffusing sparger
• Filtered airflow ensures aseptic conditions
• Adjustable 1 16 vvm gas flow optionally fitted with mass flow meter

4. Dosing & Control

• Four peristaltic pumps bring nutrients, antifoam, acid/base
• Sensor feedback loops control dosing automatically
• Precise bioprocessing with minimal manual adjustment

5. Sampling & Harvest

• Manual sampling valve allows sterile sample extraction
• Top and bottom sterilizable valves allow draining out of tanks completely
• Optional automatic harvest valves with tight dead-zone discharge

6. Monitoring & Data Export

• Siemens interface with live plots, trend views, alarm logs
• Export patterns for QC, validation, or Six Sigma programs
• Multi-language support and future customization ready

Elevating Your Lab

Equipped with the Stainless fermenter 100 Liter BLBIO-100SJA changes your working processes:

• Centralize ops with a compact, data-driven system
• Precisely repeat protocols across runs and teams
• Scale processes with minimal risk and maximum control
• Support complex biology with configurable ports and dosing loops
• This isn’t just a fermenter, it’s a bioprocess command center.

Success Stories: Real-World Impact

• Vaccine developer:Able to scale-up, going over from 20l to 100l batches, with consistent yields and good quality.
• Enzyme producer:Combined CO2 measurement to maximize production that led to 15 percent productivity improvement.
• Academic lab:Parallel cultures: administered two independent cultures at once with duplicate controls, doubled output and giving up time.

Заключительные мысли

The Stainless fermenter 100 Liter BLBIO-100SJA is the best pilot-scale bioreactor with more automation and data management than ever before, better distinction of process and control of this new benchmark. It is accurate, flexible and scale-up ready, fit to do useful science and be ready to scale to production.

Isn’t it about time that your laboratory had a fermenter that is as smart as you are? Have a special assessment, configuration advice or price quote made out by reaching BaiLun Bio today. Let’s elevate your fermentation, together.

Часто задаваемые вопросы (FAQ)

Q: Does it handle animal cell culture?

Yes! It is designed to CHO or HEK293 or other sensitive lines, with controlled temperature, low-shear mixing options, sterile sampling and automated foam control.

Q: Can I integrate gas blending?

Absolutely. Add a mass flow meter and CO 2 / O 2 / N 2 controls to be able to handle up to 2 vv m with CO 2 exhaust gas analysis to allow metabolic monitoring.

Q: Is cleaning straightforward?

Indeed, plus; there are polished SS316 surfaces, which prevents biofilm accumulation and sterilization is easy without SIP or CIP.

Q: How do I ensure consistent quality batches?

The repeatability, scale-up and regulatory compliance is promoted by using automated controls, data trends, alarms and exportable logs.

Q: Do you offer remote monitoring?

It is possible to configure remote control as an optional option of off-site monitoring and management.