5L In-Situ Sterilization Glass Fermenter Magnetic Mixing Bioreactor (Vertical) BLBIO-5GCAV

What is special about In-Situ Sterilization Glass Fermenter in the sea of lab-scale fermentation equipment’s? What is it that makes it, the backbone of cell culture, enzyme production and vaccine development projects that researchers and biotech teams around the globe are choosing? Let’s explore in detail.

A Versatile Fermentation System Tailored for Innovation

Imagine a miniature fermentation device that can get no less versatile or useful. That’s exactly what the 5L In-Situ Sterilization Glass Fermenter Magnetic Mixing Bioreactor (Vertical) BLBIO-5GCAV delivers. This system accommodates running of batch processes, fed-batch cultures as well as developing new protocols. But what truly sets it apart?

Its capacity to combine important technologies under a single vertical, space consuming system. Sight inspection of the processes by the glass vessel, stainless steel quality, and a magnetic mixing system that provides zero chances of contamination succession, all are incorporated into this equipment.

Wondering whether this may be the ideal solution to making your lab more efficient when it comes to handling complex bioprocesses?

Key Technical Features of 5L In-Situ Sterilization Glass Fermenter

Let’s dive into the heart of this bioreactor’s engineering. All the details are selected to provide the maximum control over the processes, reduce the chances of contamination, and increase the efficiency:

Fermenter Technical Parameters:

Parameter	Description
Total volume	5L,10L,15L,20L,30L,40L etc.
Working volume	40%~70%
Tank	Glass wall with stainless steel lid and bottom, heating from jacket bottom.
Stirring system	Mechanical drive(top) or Magnetic drive(top/bottom), 3 six-blade paddle and 1 foam breaker, each paddle height adjustable. Mix speed: 50~1000rpm/50-400rpm
Sterilization	Sterilization in situ (SIP), manual
Gas control	Control by rotor meter, air flow 1-2vvm.
Feeding	Automatically feeding by peristaltic pump
Anti-foam control	Automatically add antifoamer by peristaltic pump
Temperature control	Auto-control by program, electric heating range water source add 5℃ to 70℃
PH control	PH 2.00-12.00±0.1, auto-control adding acid/base by peristaltic pump, pH sensor from Hamilton/Mettler, Switzerland.
DO control	0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen.
Sampling	Manual sampling
Control parameters	10 or 15 inch touch screen , Siemens PLC with control parameters (stirring, pH, DO, temperature, feeding, alarm, gas etc.), data analysis, data record, data output, language(RU/EN/CN) and other customized functions
Optional configuration	Remote control, Mass flow meter(auto control gas), O2/N2/CO2, gas(CO2) exhaust analysis, Level sensor, Turbidity(OD) sensor, ORP sensor, Weighting system, Live cell sensor（Biomass）, Printing, Siemens touch screen, etc.

Magnetic Mixing: Zero Contamination, Gentle Agitation, the Power of Magnetic Mixing

At the center of the 5L In-Situ Sterilization Glass Fermenter Magnetic Mixing Bioreactor (Vertical) BLBIO-5GCAV is its magnetic mixing technology. Have you ever experienced some problems with mechanical seals, leakages, or contamination threats? Here, those concerns disappear.

The magnetic coupling ensures:

• Completely sealed stirring, no mechanical seal, that is no leakage channels.
• Adjustable speed control, smooth and suited with delicate cells as CHO cells or insect cells.
• Minimal shear force, protecting sensitive cultures.

Doesn’t this sound like the reliability you’ve been seeking?

Flexible Gas and Feeding Control for Perfect Growth Conditions

In-Situ Sterilization Glass Fermenter maintains your culture environment at an optimal degree of stability with its automated peristaltic pumps and rotor meter:

• Precisely adds acid, base, nutrients, and antifoam.
• Regulates gas flow for aerobic or anaerobic cultures.

When high-performance development processes are involved, there is a possibility to integrate optional mass flow meters and exhaust gas analyzers.

Could such control reduce batch variability and improve yield?

Advanced Control System: More Than Just Automation

The complex processes are made simple using a Siemens PLC and 10 or 15-inch touchscreen interface in the control system:

• Real-time monitoring of critical parameters (pH, DO, temperature, stirring speed).
• Built-in data logging and reporting tools.
• Alarms and notifications for deviations.
• Language options to suit global teams.

What would happen to this data when it was automatically sorted and ready to be exported to reports or audits?

Sterilization in Place (SIP): Simplicity Meets Safety

The SIP feature will enable the vessel to sterilize without relocating it to a separate autoclave. This offers:

• Reduced contamination risk.
• Faster turnaround between batches.
• Less manual handling.

What would let your lab be more productive through partaking in faster sterilization cycles?

Compact Vertical Design: Big Benefits in Small Spaces

In many labs, bench space is limited. This vertical design means:

• Small footprint without sacrificing working volume.
• Better integration into crowded lab benches.
• The glass wall gave clear view of the culture.

Now think of how this would save space on other equipment.

Applications Spanning Research to Production

The 5L In-Situ Sterilization Glass Fermenter Magnetic Mixing Bioreactor (Vertical) BLBIO-5GCAV isn’t limited to a single type of fermentation. It’s designed for:

• Animal vaccine production:Rabies, Avian influenza, Tetanus, etc.
• Human vaccine development:Hepatitis B, Meningitis, Diphtheria, etc.
• Enzyme and protein production.
• Growing/growth of mammalian cells, plant cells, bacteria, yeast, fungi, and algae.
• Research into new antibiotics or food additives.

Would saving time and investment on your team in having one system to so many applications?

Visual Process Insight for Confidence and Quality

The fact that it has a partial glass structure implies it is not only sensors you depend on. See:

• Mixing patterns.
• Foam formation.
• Unexpected changes in culture appearance.

Have you ever desired to be able to look inside your reactor, without opening it? This bioreactor makes it possible.

Data Driven Decisions: Batch After Batch

Data logging and export means you can:

• Analyze trends over time.
• Troubleshoot processes.
• Prove consistency to regulators.

Isn’t reliable data the backbone of process optimization?

Ready for Future Upgrades?

Thanks to modular design, you can add:

• Mass flow meters.
• Biomass sensors.
• Exhaust gas analysis.
• And more.

Does it feel good not to know that your equipment can become obsolete?

Engineered for Trust and Compliance

In-Situ Sterilization Glass Fermenter is designed on an international standard by using sensors supplied by Hamilton/Mettler, Siemens PLC, stainless steel and borosilicate glass components. Global biotech companies trust these brands every day.

What is the significance of trust in long-term career projects in the equipment supplier?

Easy to Learn, Easy to Use

Thanks to:

• Menu-driven interfaces.
• Color-coded parameters.
• Multilingual screens.
• New users can learn quickly, and training becomes simpler.

Do you suppose that your team needs less time in training: will it allow you to run experiments faster?

Supports Modern Bioprocessing Strategies

Ranging between perfusion to high-density fed-batch, this system is capable of supporting more sophisticated processes and thus is future-proof in:

• Cell line development.
• Vaccine strain optimization.
• Recombinant protein expression studies.

Do you think alternative approaches can make your research laboratory unique in this competitive world?

Custom Solutions for Unique Processes

Every lab is different, so optional configurations include:

• Gas mixing enhancements.
• Weight systems.
• Live cell sensors.
• ORP and turbidity monitoring.

Do you think this degree of customization would fit your vision of the research?

Why BaiLun Bio?

Beyond the equipment, you gain:

• Expert consultation during selection.
• Training and support.
• Access to spare parts and upgrades.

Would it not be nice to work with a partner who has an interest in your process management?

Reliable Sampling and Harvesting

The design includes:

• Manual sampling valve, easy and sterile.
• Smooth-bottom design for complete harvest.

Could more complete harvesting help improve your yields?

Designed for Scale-up and Technology Transfer

Begin on a 5L scale and then bring your process to pilots and production with the same essential technologies and sensors. This eases:

• Process validation.
• Scale-up studies.
• Technology transfer to production partners.

Would this not help reduce risks between lab to plant?

In Conclusion: Your Partner in Innovation

The 5L In-Situ Sterilization Glass Fermenter Magnetic Mixing Bioreactor (Vertical) BLBIO-5GCAV is more than equipment. It’s a platform:

• Built for consistency.
• Designed for insight.
• Supported for growth.

This bio reactor is ready to assist your lab to be innovative, optimized and a leader.

Contact BaiLun Bio today and see how it will become part of your workflow. Let’s unlock your research and production potential together.