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15000L Scale Up Industry Bioreactor
15000L Scale Up Industry Bioreactor

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15000L Large Scale Bioreactor for Industrial Fermentation

Bailun’s 15000L Large Scale Bioreactor is designed for large-scale industrial biotechnology production and advanced fermentation applications. Featuring a high-quality stainless steel vessel, intelligent PLC automation system, and precise process control technology, the bioreactor delivers stable, reproducible, and efficient cultivation conditions for industrial microbial fermentation and bioprocess manufacturing.

The 15000L industrial large scale bioreactor is widely used in biotechnology, pharmaceutical, vaccine, food & beverage, enzyme, probiotics, synthetic biology, agricultural biotechnology, and industrial bioengineering industries. It supports pilot-scale process optimization, industrial fermentation scale-up, and commercial bioprocess manufacturing applications.

To ensure stable industrial operation, the system can be integrated with supporting equipment including:

  • Chiller Systems

  • Air Compressors

  • Steam Generators

  • CIP Cleaning Systems

  • SIP Sterilization Systems

  • Exhaust Treatment Systems

  • Industrial Water Treatment Systems

The integrated solution improves fermentation consistency, industrial productivity, automation efficiency, and long-term operational reliability.

Applications of 15000L Large Scale Bioreactor

The 15000L industrial bioreactor system is suitable for a wide range of industrial biotechnology applications.

Industrial Fermentation Applications

  • Microbial Fermentation

  • Precision Fermentation

  • Probiotic Production

  • Organic Acid Fermentation

  • Industrial Enzyme Production

  • Yeast Cultivation

  • Amino Acid Fermentation

Pharmaceutical & Biotech Applications

  • Vaccine Production

  • Biopharmaceutical Fermentation

  • Recombinant Protein Expression

  • Mammalian Cell Culture

  • Synthetic Biology Production

  • Industrial Cell Culture

Food & Agricultural Applications

  • Food Ingredient Fermentation

  • Beverage Fermentation

  • Agricultural Biotechnology

  • Biofertilizer Production

  • Biopesticide Production

  • Functional Food Fermentation

Scale-Up & Commercial Production

  • Pilot-Scale Process Transfer

  • Industrial Bioprocess Production

  • Fermentation Optimization

  • Commercial Biotechnology Manufacturing

  • Continuous Production Operation

The system supports both industrial fermentation scale-up and long-term commercial biotechnology production.

Advantages of 15000L Large Scale Bioreactor Technology

Industrial Stainless Steel Vessel Design

The bioreactor adopts a high-quality stainless steel vessel structure with excellent hygienic performance and industrial durability.

Advantages include:

  • Excellent corrosion resistance

  • Long operational lifespan

  • Easy cleaning and sterilization

  • Mirror-polished internal surface

  • Reduced contamination risk

  • Suitable for industrial sterile fermentation processes

Optional SS304 and SS316L stainless steel materials are available according to different industrial process requirements.

The industrial vessel structure is optimized for continuous fermentation operation and large-scale biotechnology production environments.

Intelligent Automated Process Control

The system supports automatic monitoring and control of critical process parameters:

  • Temperature

  • pH

  • Dissolved Oxygen (DO)

  • Agitation Speed

  • Aeration Rate

  • Foam Level

  • Pressure Control

  • Feeding Control

The intelligent automation system ensures stable and reproducible fermentation performance during industrial biotechnology production.

Advanced PLC Automation System

The system supports fully automatic industrial fermentation management.

Functions include:

  • PLC automatic control

  • Siemens touchscreen optional

  • Real-time process monitoring

  • Historical data storage

  • Batch report generation

  • Alarm protection system

  • Trend analysis

  • SCADA software optional

  • Remote monitoring optional

  • MES integration optional

  • 21 CFR Part 11 optional

The automation system significantly improves industrial process efficiency, production consistency, and operational safety.

Optimized Industrial Fermentation Performance

The bioreactor is designed for efficient oxygen transfer, stable mixing, and industrial-scale productivity.

Benefits include:

  • Efficient mass transfer capability

  • Uniform nutrient distribution

  • Stable agitation performance

  • Excellent oxygen transfer efficiency

  • Reduced contamination risk

  • Reliable long-term industrial operation

  • Suitable for industrial scale-up transfer

The system is ideal for scaling laboratory and pilot-scale biotechnology processes into commercial manufacturing.

Key Features of Bailun 15000L Large Scale Bioreactor

Industrial Stainless Steel Vessel System

  • 15000L stainless steel vessel

  • SS304 / SS316L

  • Jacketed vessel structure

  • Thermal insulation optional

  • Mirror-polished internal surface

  • Industrial-grade structural strength

Advanced Agitation & Aeration

  • Multi-stage impeller design

  • Adjustable agitation speed

  • Efficient oxygen transfer capability

  • Stable airflow distribution

  • Multi-gas mixing optional

  • Low-shear mixing optional

Sterility and Contamination Control

  • SIP sterilization system optional

  • CIP cleaning system optional

  • Sterile gas filtration

  • Aseptic sampling system

  • Closed fermentation environment

  • Reduced contamination risk

Intelligent Monitoring Functions

  • Real-time process display

  • Automatic process control

  • Historical data storage

  • Alarm and safety protection

  • Batch management system

  • Remote access optional

Integrated Supporting Equipment Solutions

Bailun provides complete turnkey fermentation system solutions including:

Chiller System

Used for precise fermentation temperature control during industrial production.

Air Compressor

Provides stable compressed air supply for aeration and oxygen transfer.

Steam Generator

Supports industrial sterilization and SIP operation.

CIP Cleaning System

Automatic cleaning system for hygienic operation and reduced downtime.

Exhaust Treatment System

Optional exhaust filtration and biosafety treatment system for industrial applications.

Integrated supporting systems simplify installation, improve operational stability, and reduce maintenance workload.

Customizable 15000L Large Scale Bioreactor Solutions

Bailun provides fully customized industrial fermenter systems according to different biotechnology production requirements.

Vessel Options

  • SS304 stainless steel

  • SS316L stainless steel

  • Jacketed heating/cooling structure

  • Thermal insulation system

Agitation Options

  • Rushton impeller

  • Marine impeller

  • Paddle impeller

  • High-efficiency industrial mixing system

Sensor Options

  • Turbidity OD sensor (Optical density)

  • ORP sensor

  • Foam sensor

  • Biomass sensor

  • CO2 exhaust analysis

  • Level sensor

Automation Expansion

  • PLC automation

  • SCADA software

  • Remote monitoring

  • Data logging system

  • MES integration optional

  • 21 CFR Part 11 optional

Advantages of Bailun Industrial Large Scale Bioreactor Systems

  • Industrial-grade stainless steel manufacturing

  • Stable and reproducible fermentation performance

  • Strong engineering customization capability

  • Optimized for industrial biotechnology production

  • Reliable automation and process control

  • Integrated supporting equipment solutions

  • Global technical support and engineering services

Technical Specifications of 15000L Large Scale Bioreactor

Parameter

Specification

Total Volume

15000L

Working Volume

4500–12000L

Vessel Material

SS304 / SS316L

Agitation Type

Mechanical Agitation

Control System

PLC / Siemens HMI Optional

Temperature Control

Automatic

pH Control

Automatic

DO Control

Automatic

Anti-foam Control

Automatic

Aeration System

Air Flow 1vvm, Multi-gas Aeration Optional

Sterilization Method

SIP Automatic

Cleaning System

CIP by Spray Ball

Power Supply

380V / 50–60Hz

Applications

Industrial Fermentation / Bioprocess Production

Why Choose Bailun

Bailun is a professional manufacturer of industrial fermenters and large scale bioreactor systems for biotechnology, pharmaceutical, food, and bioengineering industries.

Why customers choose Bailun:

  • Professional fermentation engineering experience

  • High-quality stainless steel manufacturing capability

  • Strong process customization support

  • Stable industrial automation systems

  • Competitive pricing and fast delivery

  • Global installation and technical support

  • Reliable after-sales engineering service

  • Complete turnkey fermentation solutions

Frequently Asked Questions

What is a 15000L large scale bioreactor?

A 15000L large scale bioreactor is a large industrial fermentation system used for biotechnology production, microbial cultivation, and industrial bioprocess manufacturing.

What industries can use the 15000L bioreactor?

The system is suitable for biotechnology, pharmaceutical, vaccine, enzyme, probiotic, food, beverage, and industrial fermentation industries.

Does the system support automatic control?

Yes. The system supports PLC automation, Siemens touchscreen operation, SCADA software, remote monitoring, and industrial data management functions.

Can the system support SIP and CIP functions?

Yes. Optional SIP sterilization and CIP cleaning systems are available for industrial hygienic fermentation operation.

Can the bioreactor be customized?

Yes. Bailun provides customized vessel structures, agitation systems, gas control systems, automation configurations, and sensor solutions.

Request a Quote

Looking for a reliable 15000L large scale bioreactor for industrial fermentation and biotechnology production?

Contact Bailun today for:

  • Customized industrial bioreactor solutions

  • Technical consultation

  • Detailed quotation

  • Fermentation process support

  • Global shipping and technical services

Our engineering team is ready to support your industrial fermentation and bioprocess production projects worldwide.

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