GMP Vaccine Bioreactor Manufacturer for Biopharmaceutical Production
25+ Years Bioprocess Experience
Exported to 30+ Countries
CE / ISO / ASME Certified
Trusted by Vaccine Manufacturers
Our GMP Vaccine Bioreactor Solutions
We offer bioreactors (fermenters), animal cell bioreactors, bioreactor shakers, biological shakers, bottle rockers, and control systems, and recognize validation services are essential for meeting regulatory and operational requirements of fermenters and bioreactors.
GMP-Compliant Design
FDA & GMP-oriented structure
Hygienic dead-leg-free piping
Full validation documentation support
Precise Process Control
Advanced PLC automatic control
Real-time pH / DO / temperature monitoring
Stable gas flow & agitation control
Sterile SIP / CIP System
Fully automatic SIP sterilization
Integrated CIP cleaning station
Aseptic feeding and sampling system
Pharmaceutical Grade Materials
SUS316L stainless steel vessel
Internal mirror polishing Ra ≤ 0.4μm
High clean ability and corrosion resistance
Data Integrity & Automation
Audit trail & electronic records
SCADA / MES integration optional
Recipe management and batch recording
One-stop Vaccine Production Solutions
Upstream & downstream integration
Chiller / steam generator support
Customized utility system design
GMP Vaccine Bioreactor Applications
We offer bioreactors (fermenters), animal cell bioreactors, bioreactor shakers, biological shakers, bottle rockers, and control systems, and recognize validation services are essential for meeting regulatory and operational requirements of fermenters and bioreactors.
| Parameter | Description |
| Total volume | 5L~15KL |
| Working volume | 30%~80% |
| Polishing | Electrolytic polishing, precision: 0.2-0.4um. |
| Stirring system | Mechanical drive or Magnetic drive, 3 height adjustable six – blade stirrerStir speed: 50~1000rpm/50-350rpm |
| Sterilization | On-site sterilization(SIP) by auto control |
| Clean | Clean in place (CIP) by spray ball |
| Aeration flow | Multi-way ventilation. Auto control by mass flow meter, 1vvm |
| Feeding | Automatically feeding by fixed peristaltic pump (standard)Variable speed peristaltic pump(optional) |
| Anti-foam control | Automatically add antifoam by peristaltic pump |
| Temperature control | Auto-control, electric heating range: water source add 5℃ to 70℃ |
| PH control | 2.00-12.00±0.05pH, auto-control by adding acid and base, pH sensor (Hamilton/Mettler, Switzerland) |
| DO control | 0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen. |
| Sampling valve | Can sterilization separately, manual |
| Harvest | Zero dead zone bottom valve, can sterilization separately, manual |
| Weight system | Mettler-Toledo, Switzerland |
| Pressure | Auto control, BD Germany pressure transmitter or Lambert differential pressure liquid level gauge. |
| Exhaust | Have condenser before exhaust, control by diagram valve / Proportional control valve. |
| Control parameters | 10in touch screen, Siemens PLC control system with control parameters (stirring, pH, DO, temperature, feeding, gas etc.), data analysis, data logging, data output and printing, overrun alarm, language switching and other functions |
| Optional configuration | O2/N2/CO2 gas control, Level sensor, OD sensor, Turbidity sensor, ORP sensor, Weight system, Live cell sensor etc. |
Why Not Other Suppliers
Customer Projects
Vaccine Production Center
Biopharmaceutical Company
National Biotechnology Institute
Vaccine Production Company
