Screen High Flux Liquid Handing System is to partition single nucleic acid template into separate reaction chambers and performs a single molecule quantification by PCR amplification and fluorescence signal detection. The digital PCR technology does not reply on neither Ct values nor standard calibration curves, and has extremely high sensitivity, precision, and excellent repeatability. It is an absolute quantitative analysis technology that transcends real-time PCR.
150L Stainless Steel Mammalian Cell Bioreactor for Research & Pilot-Scale Bioprocessing
Bailun’s 150L Stainless Steel Mammalian Cell Bioreactor is designed for pilot-scale mammalian cell cultivation, suspension cell culture, and biopharmaceutical process development. Featuring a high-quality SS316L stainless steel vessel, low-shear agitation technology, and advanced automation platform, the system provides stable and optimized cultivation conditions for sensitive mammalian cells and biologics production.
The 150L stainless steel mammalian cell bioreactor is widely used in biotechnology companies, pharmaceutical R&D centers, vaccine development laboratories, universities, CDMO facilities, and pilot-scale biologics manufacturing projects.
Applications of 150L Stainless Steel Mammalian Cell Bioreactor
The 150L mammalian cell bioreactor is suitable for a wide range of pilot-scale and research applications, including:
Mammalian Cell Culture
Suspension Cell Culture
CHO Cell Culture
HEK293 Cell Culture
Hybridoma Cell Culture
Recombinant Protein Expression
Monoclonal Antibody (mAb) Production
Vaccine Development
Stem Cell Research
Cell Therapy Process Development
The system is ideal for pilot-scale process optimization and scale-up studies in biopharmaceutical production.
Advantages of Stainless Steel Mammalian Cell Bioreactor
High-Quality SS316L Stainless Steel Vessel
The bioreactor uses premium SS316L stainless steel materials with excellent corrosion resistance and hygienic performance.
Advantages include:
Long operational lifespan
Excellent corrosion resistance
Easy cleaning and sterilization
GMP-compatible hygienic structure
High structural stability
The stainless steel vessel is suitable for repeated pilot-scale operation and biopharmaceutical process development.
Low Shear Agitation Technology
Sensitive mammalian cells require gentle cultivation conditions. The bioreactor uses optimized low-shear agitation technology to minimize cell damage.
Benefits include:
Improved cell viability
Reduced shear stress
Stable suspension conditions
Better culture consistency
Enhanced protein expression efficiency
Suitable for CHO cells, HEK293 cells, hybridoma cells, and other suspension mammalian cells.
Precise Environmental Control
The system supports accurate monitoring and control of critical cell culture parameters.
Controlled parameters include:
Temperature
pH
Dissolved Oxygen (DO)
Agitation speed
Gasflow: Air/CO2/N2/O2
Foam level
Pressure
This helps maintain stable cell growth conditions and improves process reproducibility.
Efficient Oxygen Transfer Performance
The optimized aeration and agitation system improves oxygen transfer while minimizing foam and turbulence.
Advantages include:
Stable dissolved oxygen levels
Efficient nutrient distribution
Improved cell growth performance
Enhanced productivity
Suitable for high-density mammalian cell culture applications.
Key Features of Bailun 150L Stainless Steel Mammalian Cell Bioreactor
SS316L Vessel Construction
The system uses precision-manufactured SS316L stainless steel vessels designed for biopharmaceutical applications.
Features include:
Electropolished internal surface
Hygienic stainless steel structure
Excellent pressure resistance
Easy cleaning and sterilization
Long operational lifespan
Optional configurations include:
Jacketed vessel system
Double mechanical seal
Magnetic agitation system
GMP upgrade configuration
Intelligent Automation Control System
The 150L stainless steel mammalian cell bioreactor supports advanced automation and monitoring systems.
Optional control configurations:
Siemens PLC controller
Touchscreen HMI
SCADA system
Remote monitoring
21 CFR Part 11 support
Monitoring functions include:
Real-time parameter display
Data recording
Alarm system
Trend analysis
Batch report generation
This improves process consistency and operational efficiency.
Optimized Agitation & Aeration System
The system provides stable mixing and oxygen transfer for mammalian cell cultivation.
Features include:
Low-shear impeller design
Adjustable agitation speed
Precise airflow control
Uniform nutrient distribution
High oxygen transfer efficiency
Suitable for suspension cell culture and recombinant protein production.
GMP-Compatible Hygienic Design
The system supports GMP-oriented pilot-scale biopharma applications.
Optional GMP features include:
SIP sterilization system
CIP cleaning system
Aseptic sampling system
Sterile feed addition system
Electronic batch recording
Suitable for vaccine research and regulated biologics production environments.
Designed for Pilot-Scale Cell Culture Development
The 150L mammalian cell bioreactor is ideal for:
Development Stage | Application |
|---|---|
Laboratory Research | Process development |
Pilot-Scale Production | Scale-up optimization |
Biopharma Research | Protein expression |
Vaccine Development | Cell cultivation studies |
CDMO Projects | Pilot manufacturing |
The system supports smooth scale-up from laboratory research to pilot-scale biologics production.
Sterility and Contamination Control
Reliable sterility management is essential for mammalian cell culture applications.
Sterility features include:
Sterile gas filtration
Aseptic sampling ports
Closed cultivation environment
Sterile inoculation connections
SIP sterilization optional
CIP cleaning system optional
These features help minimize contamination risk and improve process reliability.
Customizable Mammalian Cell Bioreactor Solutions
Bailun provides customized mammalian cell culture bioreactor systems according to customer process requirements.
Vessel Options
SS316L stainless steel vessel
Jacketed vessel system
GMP vessel configuration
Agitation Options
Low-shear impeller
Marine impeller
Magnetic agitation system
Sensor Options
ORP sensor
Viable cell sensor optional
OD sensor/Turbidity
Level sensor
Biomass Live cells probe
Automation Expansion
PLC automation
SCADA integration
Data logging system
MES/ERP integration
Remote monitoring
Advantages of Bailun Stainless Steel Bioreactor Systems
Professional Biopharma Engineering
Bailun specializes in mammalian cell bioreactor and fermentation systems for biotechnology, pharmaceutical, and biopharma applications.
Flexible Customization Capability
We provide customized vessel structures, control systems, agitation configurations, and automation solutions.
Stable Cell Culture Performance
Optimized mixing and aeration systems improve cultivation stability and protein expression efficiency.
Global Technical Support
Bailun provides worldwide support including:
Installation
Commissioning
Technical consultation
Operator training
After-sales service
Technical Specifications of 150L Stainless Steel Mammalian Cell Bioreactor
Parameter | Specification |
|---|---|
Total Volume | 150L |
Working Volume | 45–120L |
Vessel Material | stainless steel 316L, Jacket 304 stainless steel Insulation: Rock wool/Aluminum silicate |
Agitation Type | Low-shear mechanical agitation |
Control System | PLC / HMI / SCADA optional |
Temperature Control | Automatic |
pH Control | Automatic |
DO Control | Automatic |
Gas control | Air, N2,O2,CO2 |
Sterilization Method | SIP / CIP optional |
Applications | Mammalian Cell Culture / Biopharma Research |
Why Choose Bailun
Bailun is a professional manufacturer of mammalian cell culture bioreactor and fermentation systems for laboratory, pilot, and industrial-scale applications.
Why customers choose Bailun:
Strong engineering capability
Flexible OEM/ODM customization
High-quality manufacturing
GMP-compatible system design
Competitive global pricing
Fast delivery
Global technical support
Rich biopharma project experience
Frequently Asked Questions
What is the main application of a 150L stainless steel mammalian cell bioreactor?
The system is mainly used for pilot-scale mammalian cell culture, biologics development, vaccine research, and biopharmaceutical process scale-up.
Is the system suitable for CHO cell culture?
Yes. The low-shear agitation system is suitable for CHO cells, HEK293 cells, hybridoma cells, and other suspension mammalian cells.
Does the system support GMP applications?
Yes. Optional GMP-oriented features include SIP, CIP, aseptic sampling, electronic batch recording, and 21 CFR Part 11 support.
Can the system support recombinant protein production?
Yes. The system is widely used for recombinant protein expression and monoclonal antibody production research.
Can the bioreactor be customized?
Yes. Bailun provides customized vessel structures, sensors, agitation systems, and automation solutions according to customer requirements.
Request a Quote
Looking for a reliable 150L stainless steel mammalian cell bioreactor for pilot-scale biopharma research?
Contact Bailun today for:
Customized mammalian cell culture solutions
Technical consultation
Detailed quotation
Pilot-scale process development support
Global technical services