20L Airlift Bioreactor

20L Airlift Bioreactor for Laboratory & Pilot Bioprocessing

Bailun’s 20L Airlift Bioreactor is designed for low-shear cell culture, microbial fermentation, algae cultivation, and pilot-scale bioprocess development. Compared with traditional stirred tank bioreactors, the airlift bioreactor uses pneumatic circulation instead of mechanical agitation, providing gentle mixing and efficient oxygen transfer for sensitive biological systems.

The 20L airlift bioreactor is widely used in biotechnology laboratories, pharmaceutical research institutes, universities, and pilot bioprocess facilities requiring stable and scalable cultivation environments.

Applications of 20L Airlift Bioreactor

The 20L airlift bioreactor is suitable for various biological and fermentation applications, including:

• Mammalian Cell Culture

• Microbial Fermentation

• Algae Cultivation

• Probiotic Fermentation

• Recombinant Protein Expression

• Enzyme Production

• Plant Cell Culture

• Suspension Cell Culture

• Biopharmaceutical Research

• Pilot-Scale Bioprocess Development

The low-shear environment makes the system particularly suitable for sensitive cells and shear-sensitive microorganisms.

Advantages of Airlift Bioreactor Technology

Compared with mechanically stirred bioreactors, airlift bioreactors provide several important advantages.

Low Shear Stress

The system uses air circulation instead of high-speed impellers, reducing mechanical damage to cells.

Benefits include:

• Improved cell viability

• Reduced shear stress

• Better suspension stability

• Suitable for delicate biological cultures

High Oxygen Transfer Efficiency

The airlift circulation design improves gas-liquid mass transfer and oxygen distribution throughout the vessel.

Advantages include:

• High oxygen transfer rate

• Uniform dissolved oxygen distribution

• Improved nutrient circulation

• Enhanced culture efficiency

Reduced Energy Consumption

Without large mechanical agitation systems, airlift bioreactors consume less energy during operation.

This helps reduce:

• Operating costs

• Heat generation

• Maintenance requirements

Simple and Reliable Structure

The simplified internal structure reduces contamination risk and improves cleaning efficiency.

Key advantages:

• Fewer moving parts

• Lower maintenance

• Easier sterilization

• Improved operational reliability

Key Features of Bailun 20L Airlift Bioreactor

Advanced Airlift Circulation Design

The bioreactor adopts an optimized riser/downcomer circulation structure for stable liquid flow and efficient gas transfer.

Design features include:

• Uniform circulation pattern

• Stable mixing performance

• Efficient oxygen distribution

• Low foaming tendency

The system is suitable for both aerobic and microaerobic cultivation processes.

High-Quality Vessel Construction

Bailun provides high-quality vessel materials and precision manufacturing for laboratory and pilot applications.

Available configurations include:

• Glass airlift bioreactor

• Stainless steel airlift bioreactor

• Hybrid glass-stainless systems

Optional vessel features:

• Jacketed temperature control

• Borosilicate glass vessel

• SS316L stainless steel components

• Electropolished internal surfaces

Intelligent Process Control System

The 20L airlift bioreactor can be equipped with a fully automated control system for precise process management.

Controlled parameters include:

• pH

• Dissolved Oxygen (DO)

• Temperature

• Airflow

• Pressure

• Foam level

Optional automation systems:

• PLC controller

• Touch screen HMI

• SCADA system

• Remote monitoring

This helps improve process consistency and operational efficiency.

Optimized for Low-Shear Cell Culture

The airlift bioreactor is ideal for sensitive biological systems that require gentle mixing conditions.

Suitable cultures include:

• Mammalian suspension cells

• Hybridoma cells

• Plant cells

• Algae cultures

• Shear-sensitive microorganisms

The low turbulence environment helps improve cell growth and product yield.

Designed for Laboratory and Pilot-Scale Applications

The 20L airlift bioreactor is suitable for:

The scalable design supports process transfer to larger airlift bioreactor systems.

Sterility and Contamination Control

Sterility is critical in bioprocessing applications. Bailun’s airlift bioreactor incorporates multiple aseptic design features.

Sterility features include:

• Closed cultivation system

• Sterile gas filtration

• SIP sterilization option

• Aseptic sampling ports

• Sterile inoculation connections

• Condensation exhaust management

These features help minimize contamination risk and improve process stability.

Customizable Airlift Bioreactor Solutions

Different biological processes require different configurations. Bailun offers customized airlift bioreactor systems based on customer requirements.

Vessel Options

• Glass vessel

• Stainless steel vessel

• Jacketed vessel system

Aeration Configuration

• Ring sparger

• Microsparger

• Customized gas distribution system

Sensor Options

• pH sensor

• DO sensor

• ORP sensor

• Foam sensor

• Biomass monitoring

Automation Expansion

• PLC automation

• SCADA integration

• Remote monitoring

• Data logging system

Advantages of Bailun Airlift Bioreactor Systems

Professional Bioprocess Engineering

Bailun specializes in bioreactor and fermentation systems for biotechnology, pharmaceutical, and research applications.

Flexible Customization Capability

We provide customized vessel design, control systems, and process configurations according to customer needs.

Stable Process Performance

Optimized airlift circulation design ensures stable oxygen transfer and low-shear cultivation conditions.

Global Technical Support

Bailun provides worldwide technical support including:

• Installation

• Commissioning

• Operator training

• Technical consultation

• After-sales service

Technical Specifications of 20L Airlift Bioreactor

Why Choose Bailun

Bailun is a professional manufacturer of bioreactor and fermentation systems for laboratory, pilot, and industrial bioprocess applications.

Why customers choose Bailun:

• Strong engineering capability

• Flexible customization

• Competitive pricing

• High-quality manufacturing

• Fast delivery

• Global support service

• Rich bioprocess experience

Frequently Asked Questions

What is the main advantage of an airlift bioreactor?

The main advantage is low shear stress combined with efficient oxygen transfer, making it ideal for sensitive cell cultures and biological processes.

Is the 20L airlift bioreactor suitable for mammalian cell culture?

Yes. The low-shear mixing environment makes it highly suitable for mammalian suspension cell cultivation.

Can the system be sterilized?

Yes. The system supports SIP sterilization or autoclave sterilization depending on the configuration.

Can the bioreactor be customized?

Yes. Bailun provides customized vessel materials, control systems, aeration configurations, and sensor options.

What industries use airlift bioreactors?

Airlift bioreactors are widely used in biotechnology, pharmaceuticals, algae cultivation, enzyme production, and biopharmaceutical research.

Request a Quote

Looking for a reliable 20L airlift bioreactor for laboratory or pilot-scale bioprocessing?

Contact Bailun today for:

• Customized airlift bioreactor solutions

• Technical consultation

• Detailed quotation

• Process optimization support

• Global technical service

Our engineering team is ready to support your fermentation and cell culture projects worldwide.