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Blbio-30000SCUC
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Bailun
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30000L
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9000-24000L
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50-40
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Top Magnetic
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Gasflow Air CO2 N2 O2, pH,DO,Temperature,Antifoam,Agitation,SIP,CIP
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22-24 Weeks
30000L SS Mammalian Cell Culture Bioreactor for Industrial Biopharma Production
Bailun’s 30000L SS Mammalian Cell Culture Bioreactor is designed for large-scale mammalian cell cultivation, biologics manufacturing, and commercial biopharmaceutical production. Featuring a GMP-compatible SS316L stainless steel vessel, advanced automation platform, and optimized low-shear agitation technology, the system provides stable and aseptic cultivation conditions for high-density mammalian cell culture applications.
The 30000L stainless steel mammalian cell culture bioreactor is widely used in pharmaceutical companies, vaccine manufacturers, CDMO facilities, biotechnology enterprises, and industrial biologics production plants for monoclonal antibody manufacturing, recombinant protein expression, and suspension cell culture processes.
Applications of 30000L SS Mammalian Cell Culture Bioreactor
The 30000L industrial mammalian cell bioreactor is suitable for multiple large-scale biopharmaceutical applications:
Mammalian Cell Culture
Suspension Cell Culture
CHO Cell Culture
HEK293 Cell Culture
Monoclonal Antibody (mAb) Production
Recombinant Protein Expression
Vaccine Manufacturing
Viral Vaccine Production
Cell Therapy Process Development
Commercial Biologics Manufacturing
The system is ideal for industrial-scale biologics and pharmaceutical production.
Advantages of Stainless Steel Mammalian Cell Culture Bioreactor
GMP-Compatible SS316L Stainless Steel Vessel
The bioreactor uses pharmaceutical-grade SS316L stainless steel materials with excellent hygienic performance and corrosion resistance.
Advantages include:
GMP-compliant hygienic design
Excellent corrosion resistance
Long operational lifespan
Easy cleaning and sterilization
Stable process performance
The vessel is suitable for aseptic biopharmaceutical manufacturing environments.
Low Shear Agitation Technology
Sensitive mammalian and suspension cells require gentle cultivation conditions. The optimized agitation system minimizes shear stress while maintaining efficient mixing and oxygen transfer.
Benefits include:
Improved cell viability
Stable suspension conditions
Enhanced oxygen transfer efficiency
Improved protein expression performance
Better biologics productivity
Suitable for CHO cells, HEK293 cells, hybridoma cells, and other industrial cell culture applications.
Precise Environmental Control
The system supports accurate monitoring and control of critical biopharmaceutical production parameters.
Controlled parameters include:
Temperature
pH
Dissolved Oxygen (DO)
Agitation speed
Gasflow:Air/CO2/N2/O2
Foam level
This ensures stable and reproducible commercial production conditions.
High Oxygen Transfer Efficiency
The optimized aeration and agitation system provides efficient oxygen transfer for high-density cell culture applications.
Advantages include:
Stable dissolved oxygen levels
Uniform nutrient distribution
Enhanced cell growth performance
Improved biologics yield
Reduced foam generation
Suitable for industrial aerobic mammalian cell culture processes.
Key Features of Bailun 30T SS Mammalian Cell Culture Bioreactor
High-Quality SS316L Vessel Construction
The system uses precision-manufactured SS316L stainless steel vessels designed for pharmaceutical and biologics manufacturing applications.
Features include:
Electropolished internal surface
Hygienic sanitary structure
Pressure-resistant vessel design
Long operational lifespan
Easy cleaning and sterilization
Optional configurations include:
Jacketed vessel system
Magnetic agitation system
Double mechanical seal
GMP validation package
Intelligent Automation Control System
The 30T mammalian cell culture bioreactor supports advanced automation and monitoring systems.
Optional control configurations:
Siemens PLC controller
Touchscreen HMI
SCADA system
MES integration
Remote monitoring
21 CFR Part 11 support
Monitoring functions include:
Real-time parameter monitoring
Batch recording
Alarm system
Trend analysis
Production report generation
This improves commercial manufacturing consistency and operational efficiency.
SIP & CIP System
The bioreactor supports automatic SIP (Sterilization-In-Place) and CIP (Cleaning-In-Place) systems for aseptic pharmaceutical production.
Advantages include:
Reduced contamination risk
Faster cleaning and sterilization
Improved production efficiency
GMP-compliant operation
Reduced manual intervention
Suitable for large-scale pharmaceutical manufacturing facilities.
GMP-Oriented Hygienic Design
The system is designed according to GMP pharmaceutical manufacturing requirements.
Optional GMP features include:
Aseptic sampling system
Sterile feed addition system
Electronic batch recording
Audit trail functionality
Validation documentation (DQ/IQ/OQ/PQ)
Suitable for FDA and EMA-regulated biologics manufacturing projects.
Designed for Industrial Biopharma Production
The 30T mammalian cell culture bioreactor is suitable for:
Production Stage | Application |
|---|---|
Pilot Scale-Up | Process optimization |
Commercial Manufacturing | Biologics production |
Vaccine Production | Suspension cell culture |
CDMO Projects | Contract manufacturing |
Pharmaceutical Production | GMP biologics processing |
The system supports stable industrial-scale mammalian cell culture production.
Sterility and Contamination Control
Reliable sterility management is essential for biologics manufacturing.
Sterility features include:
SIP sterilization system
Sterile gas filtration
Aseptic sampling ports
Closed cultivation environment
Sterile inoculation system
CIP cleaning system
These features help minimize contamination risk and ensure stable commercial production.
Customizable Mammalian Cell Bioreactor Solutions
Bailun provides customized stainless steel mammalian cell culture bioreactor systems according to customer production requirements.
Vessel Options
SS316L stainless steel vessel
Jacketed vessel system
GMP pharmaceutical configuration
Agitation Options
Low-shear impeller
Marine impeller
Magnetic agitation system
Sensor Options
ORP sensor
Viable cell sensor optional
OD sensor/Turbidity
Level sensor
Biomass Live cells probe
Automation Expansion
PLC automation
SCADA integration
MES/ERP integration
Data logging system
Remote monitoring
Advantages of Bailun Industrial Bioreactor Systems
Professional Biopharma Engineering
Bailun specializes in mammalian cell culture bioreactor and fermentation systems for biotechnology, pharmaceutical, and biologics applications.
Flexible Customization Capability
We provide customized vessel structures, control systems, agitation configurations, and automation solutions.
Stable Production Performance
Optimized mixing and aeration systems improve cultivation stability and biologics production efficiency.
Global Technical Support
Bailun provides worldwide support including:
Installation
Commissioning
Technical consultation
Operator training
After-sales service
Technical Specifications of 30T SS Mammalian Cell Culture Bioreactor
Parameter | Specification |
|---|---|
Total Volume | 30,000L |
Working Volume | 9,000–2,4000L |
Vessel Material | stainless steel 316L, Jacket 304 stainless steel Insulation: Rock wool/Aluminum silicate |
Agitation Type | Low-shear mechanical agitation |
Control System | PLC / HMI / SCADA optional |
Temperature Control | Automatic |
pH Control | Automatic |
DO Control | Automatic |
Gas control | Air, N2,O2,CO2 |
Sterilization Method | SIP / Autoclave optional |
Applications | Mammalian Cell Culture / Biopharma Production |
Why Choose Bailun
Bailun is a professional manufacturer of mammalian cell culture bioreactor and fermentation systems for pilot-scale and industrial-scale pharmaceutical production.
Why customers choose Bailun:
Strong engineering capability
Flexible OEM/ODM customization
High-quality manufacturing
GMP-compatible system design
Competitive global pricing
Fast delivery
Global technical support
Rich biologics project experience
Frequently Asked Questions
What is the main application of a 30000L mammalian cell culture bioreactor?
The system is mainly used for industrial mammalian cell culture, biologics manufacturing, vaccine production, and commercial-scale pharmaceutical processing.
Is the system suitable for CHO cell culture?
Yes. The low-shear agitation system is suitable for CHO cells, HEK293 cells, hybridoma cells, and other suspension mammalian cell lines.
Does the system support GMP applications?
Yes. Optional GMP-oriented features include SIP, CIP, electronic batch recording, aseptic sampling, and 21 CFR Part 11 support.
Can the system support commercial biologics production?
Yes. The system is designed for large-scale recombinant protein expression, monoclonal antibody production, and vaccine manufacturing.
Can the bioreactor be customized?
Yes. Bailun provides customized vessel structures, sensors, agitation systems, and automation solutions according to customer production requirements.
Request a Quote
Looking for a reliable 30T SS mammalian cell culture bioreactor for industrial biopharma production?
Contact Bailun today for:
Customized mammalian cell culture solutions
Technical consultation
Detailed quotation
Commercial production support
Global technical services