Screen High Flux Liquid Handing System is to partition single nucleic acid template into separate reaction chambers and performs a single molecule quantification by PCR amplification and fluorescence signal detection. The digital PCR technology does not reply on neither Ct values nor standard calibration curves, and has extremely high sensitivity, precision, and excellent repeatability. It is an absolute quantitative analysis technology that transcends real-time PCR.
5000L Scale-Up Industry Bioreactor
Introduction
The 5000L Scale-Up Industry Bioreactor is designed for large-scale fermentation and industrial bioprocessing applications. Engineered for efficiency and scalability, this bioreactor is perfect for various fermentation processes, including food & beverage, biofuels, and other non-pharma biotech applications. With high performance, reliability, and ease of use, it supports large-scale production with consistent, reproducible results. To ensure optimal performance, the system integrates seamlessly with essential supporting equipment such as Chillers, Air Compressors, and Steam Generators.
Key Features
Large Capacity: 5000L working volume for high-yield fermentation
Efficient Scalability: Seamless transition from lab-scale to industrial-scale production
Advanced Control Systems: Precise control of temperature, pH, DO, and agitation for optimal fermentation
Robust Construction: Durable, corrosion-resistant materials SS316L/SS304 designed for long-term use
Modular Design: Customizable configurations to meet specific industrial fermentation needs
Automated Monitoring: Integrated sensors for real-time monitoring and data logging
Integrated Support Equipment: Includes Chiller, Air Compressor, and Steam Generator for full system functionality
Benefits of the 5000L Scale-Up Industry Bioreactor
High Yields: Optimized for large-volume fermentation processes to maximize productivity.
Scalability: Supports scaling from pilot projects to full-scale industrial production.
Versatile Applications: Ideal for non-pharma applications such as biofuels, food & beverage, and industrial enzymes.
Ease of Use: Simple, intuitive controls with touchscreen interface for hassle-free operation.
Efficiency: Energy-efficient design for cost-effective long-term use.
Global Support: Comprehensive service and support for installation, operation, and maintenance.
Seamless Integration: The system works in harmony with essential equipment like Chillers, Air Compressors, and Steam Generators to ensure consistent operation.
Applications
Biofuels Production: Ideal for large-scale fermentation of biofuels, including ethanol and biodiesel.
Food & Beverage Industry: Supports fermentation processes in the production of alcoholic beverages, probiotics, and food ingredients.
Industrial Enzymes: Used for the production of industrial enzymes and other bio-based chemicals.
Agricultural Products: Fermentation for the production of fertilizers, biopesticides, and other agricultural biotech products.
Technical Specifications
Working Volume: 5000L
Material: Stainless steel 316L/SS304, corrosion-resistant construction for industrial use
Control System: Siemens (or specify your system)
Sensors Included: pH, DO, Temperature, foam
Agitation: Adjustable speed for optimal fermentation performance
Power Supply: 380V, 50/60Hz (customizable based on location)
Heating/Cooling: Integrated temperature control for maintaining optimal fermentation conditions
Safety Features: Pressure relief valve, overflow protection, and emergency shutdown systems
Supporting Equipment(Optional):
Chiller: For precise temperature control during fermentation.
Air Compressor: Supplies oxygen for aeration and optimal cell growth.
Steam Generator: Provides steam for sterilization and maintaining high-temperature requirements.
Optional Configurations
Additional Sensors: Biomass, turbidity, and other specific sensors for enhanced monitoring
Automated Feeding System: For precise nutrient and substrate delivery during fermentation
Data Logging Integration: Real-time data logging and integration for seamless bioprocess management
Customized Agitation: For specific fermentation needs, including high-viscosity cultures
GMP Compliance: Optional GMP-compliant configurations for regulated environments (if needed)
Standard Bioreactor vs GMP Pharmaceutical Bioreactor Parameter Comparison
Parameter | Standard Bioreactor | GMP Pharmaceutical Bioreactor |
|---|---|---|
Tank Design | Tank + Jacket | Tank + Jacket + Insulation layer, inner surface requires electropolishing |
Sterilization Method | Sterilized, no cold spot detection validation | Sterilized, includes cold spot detection for air inlet, exhaust, seed transfer, sampling, and each sterilize line |
Volume Measurement | None | Yes,load cell/Pressure difference lever sensor (Accurate volume measurement system) |
Exhaust Control | Condensation direct discharge | Condensation, filter, heating, cold spot detection |
Agitation Type | Single-end mechanical agitation | Double-end mechanical agitation or magnetic agitation |
Feed Addition | Top needle-type injection | Four valve group, aseptic feed addition |
Inoculation | Flame-protected operation/Pump feeding | Four valve group, aseptic inoculation |
Bottom Valve | Manual | Pneumatic bottom valve |
Data Integrity | None | Audit trail functionality, electronic signatures |
Validation | FAT | 3Q/FAT/SAT full validation program |
CIP (Cleaning) | CIP tank by spray ball | Full CIP (Clean-In-Place) system |
Applications & Usage | Primarily used for research and small-scale production, suitable for exploratory research and experimental validation | Used in GMP-compliant manufacturing processes, widely used for pharmaceutical, vaccine, cell therapy production |
Design & Operation Standards | Simple design, flexible operation, focused on experimental data and scientific exploration | Strict adherence to GMP standards, ensuring traceability, consistency, and product safety |
Quality Control & Certification | Typically does not require strict certification, focused on laboratory research and small-scale validation | Must comply with strict regulatory requirements (FDA, ASME, CSA,CE, etc.), subject to regular audits and certifications to ensure compliance for market entry |
Why Choose Our 5000L Scale-Up Bioreactor?
Proven Technology: Years of experience in providing reliable and high-performance bioreactors for industrial fermentation.
Customizable: Tailored solutions to meet your unique production requirements and process parameters.
Scalable: Supports growth from pilot-scale to large-scale production, making it ideal for ongoing business expansion.
Comprehensive Support: Our team offers expert installation, training, and 24/7 global customer support to ensure your bioreactor runs smoothly.
Cost-Efficient: Designed for high throughput, energy efficiency, and reduced operating costs over time.
Full Integration: The bioreactor is designed to seamlessly work with Chillers, Air Compressors, and Steam Generators, creating a complete system for optimal fermentation.
Contact Us
For more information or to request a quote, get in touch with our team of experts. We can help you determine the best configuration and setup for your industrial fermentation needs.