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BLBIO-5000SJA
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Bailun
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5000liters
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2000-5000liters
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50-300rpm
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Mechanical/Magnetic
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pH,DO,Temperature,Antifoam,Agitation,SIP,CIP
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8-10 Weeks
5000L Scale-Up Industry Bioreactor
Introduction
The 5000L Scale-Up Industry Bioreactor is designed for large-scale fermentation and industrial bioprocessing applications. Engineered for efficiency and scalability, this bioreactor is perfect for various fermentation processes, including food & beverage, biofuels, and other non-pharma biotech applications. With high performance, reliability, and ease of use, it supports large-scale production with consistent, reproducible results. To ensure optimal performance, the system integrates seamlessly with essential supporting equipment such as Chillers, Air Compressors, and Steam Generators.
Key Features
Large Capacity: 5000L working volume for high-yield fermentation
Efficient Scalability: Seamless transition from lab-scale to industrial-scale production
Advanced Control Systems: Precise control of temperature, pH, DO, and agitation for optimal fermentation
Robust Construction: Durable, corrosion-resistant materials SS316L/SS304 designed for long-term use
Modular Design: Customizable configurations to meet specific industrial fermentation needs
Automated Monitoring: Integrated sensors for real-time monitoring and data logging
Integrated Support Equipment: Includes Chiller, Air Compressor, and Steam Generator for full system functionality
Benefits of the 5000L Scale-Up Industry Bioreactor
High Yields: Optimized for large-volume fermentation processes to maximize productivity.
Scalability: Supports scaling from pilot projects to full-scale industrial production.
Versatile Applications: Ideal for non-pharma applications such as biofuels, food & beverage, and industrial enzymes.
Ease of Use: Simple, intuitive controls with touchscreen interface for hassle-free operation.
Efficiency: Energy-efficient design for cost-effective long-term use.
Global Support: Comprehensive service and support for installation, operation, and maintenance.
Seamless Integration: The system works in harmony with essential equipment like Chillers, Air Compressors, and Steam Generators to ensure consistent operation.
Applications
Biofuels Production: Ideal for large-scale fermentation of biofuels, including ethanol and biodiesel.
Food & Beverage Industry: Supports fermentation processes in the production of alcoholic beverages, probiotics, and food ingredients.
Industrial Enzymes: Used for the production of industrial enzymes and other bio-based chemicals.
Agricultural Products: Fermentation for the production of fertilizers, biopesticides, and other agricultural biotech products.
Technical Specifications
Working Volume: 5000L
Material: Stainless steel 316L/SS304, corrosion-resistant construction for industrial use
Control System: Siemens (or specify your system)
Sensors Included: pH, DO, Temperature, foam
Agitation: Adjustable speed for optimal fermentation performance
Power Supply: 380V, 50/60Hz (customizable based on location)
Heating/Cooling: Integrated temperature control for maintaining optimal fermentation conditions
Safety Features: Pressure relief valve, overflow protection, and emergency shutdown systems
Supporting Equipment(Optional):
Chiller: For precise temperature control during fermentation.
Air Compressor: Supplies oxygen for aeration and optimal cell growth.
Steam Generator: Provides steam for sterilization and maintaining high-temperature requirements.
Optional Configurations
Additional Sensors: Biomass, turbidity, and other specific sensors for enhanced monitoring
Automated Feeding System: For precise nutrient and substrate delivery during fermentation
Data Logging Integration: Real-time data logging and integration for seamless bioprocess management
Customized Agitation: For specific fermentation needs, including high-viscosity cultures
GMP Compliance: Optional GMP-compliant configurations for regulated environments (if needed)
Standard Bioreactor vs GMP Pharmaceutical Bioreactor Parameter Comparison
Parameter | Standard Bioreactor | GMP Pharmaceutical Bioreactor |
|---|---|---|
Tank Design | Tank + Jacket | Tank + Jacket + Insulation layer, inner surface requires electropolishing |
Sterilization Method | Sterilized, no cold spot detection validation | Sterilized, includes cold spot detection for air inlet, exhaust, seed transfer, sampling, and each sterilize line |
Volume Measurement | None | Yes,load cell/Pressure difference lever sensor (Accurate volume measurement system) |
Exhaust Control | Condensation direct discharge | Condensation, filter, heating, cold spot detection |
Agitation Type | Single-end mechanical agitation | Double-end mechanical agitation or magnetic agitation |
Feed Addition | Top needle-type injection | Four valve group, aseptic feed addition |
Inoculation | Flame-protected operation/Pump feeding | Four valve group, aseptic inoculation |
Bottom Valve | Manual | Pneumatic bottom valve |
Data Integrity | None | Audit trail functionality, electronic signatures |
Validation | FAT | 3Q/FAT/SAT full validation program |
CIP (Cleaning) | CIP tank by spray ball | Full CIP (Clean-In-Place) system |
Applications & Usage | Primarily used for research and small-scale production, suitable for exploratory research and experimental validation | Used in GMP-compliant manufacturing processes, widely used for pharmaceutical, vaccine, cell therapy production |
Design & Operation Standards | Simple design, flexible operation, focused on experimental data and scientific exploration | Strict adherence to GMP standards, ensuring traceability, consistency, and product safety |
Quality Control & Certification | Typically does not require strict certification, focused on laboratory research and small-scale validation | Must comply with strict regulatory requirements (FDA, ASME, CSA,CE, etc.), subject to regular audits and certifications to ensure compliance for market entry |
Why Choose Our 5000L Scale-Up Bioreactor?
Proven Technology: Years of experience in providing reliable and high-performance bioreactors for industrial fermentation.
Customizable: Tailored solutions to meet your unique production requirements and process parameters.
Scalable: Supports growth from pilot-scale to large-scale production, making it ideal for ongoing business expansion.
Comprehensive Support: Our team offers expert installation, training, and 24/7 global customer support to ensure your bioreactor runs smoothly.
Cost-Efficient: Designed for high throughput, energy efficiency, and reduced operating costs over time.
Full Integration: The bioreactor is designed to seamlessly work with Chillers, Air Compressors, and Steam Generators, creating a complete system for optimal fermentation.
Contact Us
For more information or to request a quote, get in touch with our team of experts. We can help you determine the best configuration and setup for your industrial fermentation needs.