Engineered for Reliable Pilot-Scale Fermentation
The 700L stainless steel bioreactor is specifically designed for pilot-scale fermentation and process scale-up. It provides a stable and controllable environment for microbial and cell culture processes, ensuring consistent results from lab to production.
With industrial-grade construction and advanced automation, this system bridges the gap between laboratory research and large-scale manufacturing, helping you reduce scale-up risks and improve process reproducibility.
Key Features That Improve Fermentation Performance
Dual Gas Control System for Precise Aeration
Optional equip with multiple gas inlets (O₂, N₂, CO₂), enabling accurate control of dissolved oxygen and supporting both aerobic and anaerobic fermentation processes.
High-Efficiency Agitation & Mixing Design
Optimized impeller configuration ensures uniform mixing, improved mass transfer, and enhanced cell growth performance.
Fully Automated Control System
Integrated PLC with a user-friendly touchscreen interface allows real-time monitoring and control of key parameters such as pH, DO, temperature, agitation speed, and feeding.
CIP/SIP Sterilization Capability
Designed for clean-in-place (CIP) and sterilize-in-place (SIP), ensuring aseptic operation and compliance with industrial standards.
Modular & Scalable Design
Flexible configuration options allow easy customization and future upgrades, supporting different fermentation processes and requirements.
Applications Across Biotech & Industrial Fermentation
This 700L bioreactor is widely used in:
Microbial fermentation (bacteria, yeast, fungi)
Biopharmaceutical development and production
Enzyme and protein expression
Cell culture processes
Pilot-scale process development and optimization
It is an ideal solution for transitioning from lab-scale experiments to pilot-scale validation.
Why Choose a 100L Pilot-Scale Bioreactor?
Ideal for Process Scale-Up
A 100L bioreactor provides the perfect balance between laboratory testing and industrial production, making it a critical step in process validation.
Improved Process Consistency
Ensures that fermentation parameters remain stable during scale-up, reducing the risk of process failure.
Flexible Operation Modes
Supports batch, fed-batch, and continuous fermentation processes to meet diverse production needs.
Optimized for R&D and Pilot Plants
Designed for research institutes, biotech companies, and industrial fermentation facilities.
Technical Specifications
Total Volume: 100L
Working Volume: 30–80L
Material: SS316L stainless steel and SS304 for jacket
Agitation Type: Mechanical stirring (top or bottom driven optional)
Parameter: Temperature, pH, DO, agitation speed, airflow
Sterilization: SIP (in-situ sterilization supported)
Cleaning: CIP(in-situ cleaning in place)
Control System: PLC + touchscreen interface
Power Supply: Customizable according to region
Standard & Optional Configurations
Standard Configuration
Bioreactor vessel
Agitation system
Temperature control system
Basic sensors (pH, DO, temperature, foam)
Skid and valves
Control system (PLC + HMI)
Feeding system (4 peristaltic pumps)
Optional Configurations
Remote monitoring system
Mass flow meter(MFC)
Gas inlet (O₂ / N₂ / CO₂ / H₂ / CO)
Exhaust gas analysis (O₂ / CO₂ / CH₄ / H₂)
Level sensor
Load cell(weighting for fermentation tank / feeding)
Turbidity (OD) sensor
ORP sensor (for anaerobic cultivation)
Glucose detection
Live cell sensor (biomass)
Variable speed pump
Proportional control valve (exhaust)
Printing function
15” color touch screen
Siemens touchscreen
Robust Design for Industrial Reliability
Built with high-quality SS316L stainless steel, the bioreactor ensures excellent corrosion resistance and long service life. The system is designed to meet industrial and GMP requirements, featuring:
Hygienic design with smooth internal surfaces
Reliable sealing system (mechanical or magnetic seal optional)
Stable structure for long-term operation
Easy maintenance and cleaning
Advantages Over Conventional Bioreactors
Stainless Steel vs Glass Bioreactors
Higher durability and pressure resistance
Suitable for pilot and industrial scale
Better for long-term and high-intensity use
Pilot Scale vs Lab Scale
Enables real process validation
Reduces scale-up uncertainty
Closer to industrial production conditions
Automated vs Manual Systems
Higher precision and repeatability
Reduced human error
Improved data tracking and process control
Proven in Real Fermentation Processes
This system has been widely applied in fermentation industries including biotechnology, pharmaceuticals, food processing, and environmental engineering.
It supports a wide range of processes, from strain development to pilot-scale production, helping users accelerate commercialization.
Frequently Asked Questions
What is a 100L bioreactor used for?
It is mainly used for pilot-scale fermentation, process development, and scale-up from laboratory to industrial production.
Can this bioreactor support anaerobic fermentation?
Yes, with proper gas control and optional ORP monitoring, it can support anaerobic processes.
Is it suitable for GMP production?
The system can be designed to meet GMP requirements depending on configuration and documentation.
What control system is included?
A PLC-based automatic control system with touchscreen interface is standard.
Can the system be customized?
Yes, we provide flexible customization based on your process requirements.
Request a Quote for Your Bioprocess
Looking for a reliable 100L stainless steel bioreactor for your fermentation process?
Contact us today to get:
Detailed specifications
Customized configuration
Competitive pricing
Technical consultation from engineers
Send your inquiry now and let us help you build the right fermentation solution.